Biomarker responses of earthworms (Eisenia fetida) exposured to phenanthrene and pyrene both singly and combined in microcosms

Chemosphere
Shi-jin WuJian-meng Chen

Abstract

Microcosm studies were undertaken to relate biomarker responses to the toxicities in soil ecosystems contaminated by phenanthrene (Phe) and pyrene (Pyr), both singly and combined. Growth inhibition, enzyme activity, MDA content, sperm count, neutral-red retention time (NRRT) and annetocin and TCTP gene transcriptions were determined in earthworm Eisenia fetida exposed to Phe and Pyr, both singly and combined pollution in microcosm. Exposure to 0.5 and 2.5 mg kg(-1) Phe or 50 and 100 mg kg(-1) Pyr alone significantly decreased E. fetida growth, NRRT and sperm count. Two-way ANOVA analysis shows that the combination of these two compounds decreased growth, SOD activities, NRRT and sperm count synergistically, but increased the CAT activities and MDA content. The highest suppression rate of growth was 48.12%, the lowest levels of SOD activities and NRRT were 51.66% and 45.57% of the control, respectively. The highest increase in CAT activities and MDA content were 120.05% and 121.03% greater than that of the control when exposed to 0.5 (Phe)+100 (Pyr) mg kg(-1) soils. A clear dose-related response with exposure concentration was established for the NRRT. Real-time PCR shows that Phe and Pyr increased the expression levels of annet...Continue Reading

References

Apr 17, 1987·Science·R Wilson, E A Crouch
Jan 14, 1994·Biochemical and Biophysical Research Communications·T OumiK Nomoto
Feb 19, 1998·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·C S JewellG W Winston
Dec 3, 1999·Ecotoxicology and Environmental Safety·M S MaboetaS A Reinecke
Jul 18, 2002·Trends in Pharmacological Sciences·Edward J Calabrese, Linda A Baldwin
Feb 28, 2003·Environmental and Molecular Mutagenesis·P RajaguruK Kalaiselvi
Dec 9, 2003·Ecotoxicology and Environmental Safety·H J RickettsP Kille
Dec 23, 2003·The International Journal of Biochemistry & Cell Biology·Ulrich-Axel Bommer, Bernd-Joachim Thiele
Aug 18, 2004·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·David J SpurgeonPeter Kille
Dec 6, 2005·Ecotoxicology and Environmental Safety·S A Reinecke, A J Reinecke
May 2, 2006·Ecotoxicology and Environmental Safety·M Shuhaimi-Othman, D Pascoe
May 11, 2006·Environmental Science & Technology·F BrulleF Vandenbulcke
Dec 22, 2007·Ecotoxicology and Environmental Safety·Senlin ZhengWei Zhang
Feb 1, 2003·Environmental Toxicology and Pharmacology·Ron van der OostNico P E Vermeulen

❮ Previous
Next ❯

Citations

Sep 4, 2012·Archives of Environmental Contamination and Toxicology·Muhammad Imran KhanYingxu Chen
Feb 27, 2013·Archives of Environmental Contamination and Toxicology·Muhammad Imran KhanYingxu Chen
Mar 13, 2014·Environmental Toxicology and Pharmacology·Minling GaoXiaojun Ma
Jan 19, 2016·Environmental Science and Pollution Research International·Yuhong GaoZhenjun Sun
Oct 16, 2012·Ecotoxicology and Environmental Safety·Xiaoxia YangXiufeng Cao
Apr 30, 2015·Environmental Geochemistry and Health·Tae-Hoon NamSung-Eun Lee
Jan 21, 2015·Archives of Environmental Contamination and Toxicology·Xiang-Bo XuR J Ritchie
Oct 21, 2014·Environmental Science and Pollution Research International·Li DuJie Zhao
May 4, 2017·Ecotoxicology and Environmental Safety·Tong LiuFenglong Wang
Apr 7, 2017·Environmental Science and Pollution Research International·Zhiming ShiCongying Wang
Nov 17, 2017·Environmental Science and Pollution Research International·Wencai DaiYongming Luo
Jan 11, 2019·Environmental Science and Pollution Research International·Marija MrdakovićVesna Perić-Mataruga
May 28, 2019·Environmental Science and Pollution Research International·Yuhong GaoXuemei Li
May 16, 2015·Environmental Science and Pollution Research International·Marija MrdakovićVesna Perić-Mataruga
Jan 9, 2021·International Journal of Biological Macromolecules·Ning SunRutao Liu
Mar 27, 2020·Journal of Hazardous Materials·Yuanbo LiZhenjun Sun

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.