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Biomarkers and personalized therapy in chronic kidney diseases

Expert Opinion on Investigational Drugs

May 27, 2014

Francesco Paolo Schena

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PubMed

Abstract

Numerous clinical trials are currently evaluating new strategies to halt the progression of renal damage in patients with chronic kidney diseases (CKDs). Unfortunately, none of them have considered that the lack of response to new therapies may be due to the pharmacogenetics/pharmacogen...read more

Mentioned in this Paper

Chronic Kidney Insufficiency
Kidney
Oncology Field
Pharmacogenetics
Proteomics
Genomics
Pharmacogenomics
Individualized Medicine
High-Throughput Chemical Assays
Metabolite
1
21
Paper Details
References
  • References22
  • Citations2
123
  • References22
  • Citations2
1

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Biomarkers and personalized therapy in chronic kidney diseases

Expert Opinion on Investigational Drugs

May 27, 2014

Francesco Paolo Schena

PMID: 24857812

DOI: 10.1517/13543784.2014.922953

Abstract

Numerous clinical trials are currently evaluating new strategies to halt the progression of renal damage in patients with chronic kidney diseases (CKDs). Unfortunately, none of them have considered that the lack of response to new therapies may be due to the pharmacogenetics/pharmacogen...read more

Mentioned in this Paper

Chronic Kidney Insufficiency
Kidney
Oncology Field
Pharmacogenetics
Proteomics
Genomics
Pharmacogenomics
Individualized Medicine
High-Throughput Chemical Assays
Metabolite
1
21

Feeds With Similar Papers

Pharmacogenetics & Pharmacogenomics

Pharmacogenetics and pharmacogenomics (pgx) are rapidly growing fields that aim to elucidate the genetic basis for the interindividual differences in drug response. Here is the latest research on pharmacogenetics and pharmacogenomics.

Precision Medicine

Precision medicine is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the patient traits and specific molecular features of disease processes. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. Tools employed in precision medicine can include molecular diagnostics, imaging, and analytics

Related Papers

Biomarkers in Medicine

Use of genome-wide high-throughput technologies in biomarker development(opens in new tab)

Biomarkers in MedicineOctober 1, 2008
Sabine ClassenJoachim L Schultze
Paper Details
References
  • References22
  • Citations2
123
  • References22
  • Citations2
1

Download from

Publisher
PubMed
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