Biomarkers of in vivo fluorescence imaging in allergic airway inflammation

Molecular and Cellular Probes
Fa-Ping WangHui Mao

Abstract

Airway inflammation is a central component of the manifestation of asthma but is relatively inaccessible to study. Current imaging techniques such as X-ray CT, MRI, and PET, have advanced noninvasive research on pulmonary diseases. However, these techniques mainly facilitate the anatomical or structural assessment of the diseased lung and/or typically use radioactive agents. In vivo fluorescence imaging is a novel method for noninvasive, real-time, and specific monitoring of lung airway inflammation, which is particularly important to gain a further understanding asthma. Compared to conventional techniques, fluorescent imaging has the advantages of rapid feedback, as well as high sensitivity and resolution. Recently, there has been an increase in the identification of biomarkers, including matrix metalloproteinases, cathepsins, selectins, folate receptor-beta, nanoparticles, as well as sialic acid-binding immunoglobulin-like lectin-F to assess the level of airway inflammation in asthma. Recent advances in our understanding of these biomarkers as molecular probes for in vivo imaging are discussed in this review.

References

Sep 16, 2000·American Journal of Respiratory and Critical Care Medicine·E A KellyN N Jarjour
Jul 19, 2002·Arthritis and Rheumatism·Mary Jo TurkPhilip S Low
Dec 12, 2002·Current Opinion in Pulmonary Medicine·Elizabeth A Kelly, Nizar N Jarjour
Jun 28, 2003·Trends in Molecular Medicine·Klaus Ley
Oct 29, 2003·Current Opinion in Chemical Biology·John V Frangioni
Dec 16, 2003·Journal of Applied Physiology·Michael R Van ScottJonathan Nyce
Jun 23, 2004·American Journal of Respiratory Cell and Molecular Biology·Marc Peters-Golden
Aug 8, 2006·The Journal of Allergy and Clinical Immunology·Bérénice HerszbergJean-Pierre Lavoie
Dec 16, 2006·European Journal of Pharmacology·Dae Yong KimJai Youl Ro
Jan 20, 2007·Current Opinion in Biotechnology·Jianghong RaoHequan Yao
Jan 24, 2007·Physiological Reviews·Kendra J GreenleeFarrah Kheradmand
Mar 24, 2007·Nature Reviews. Immunology·Paul R CrockerAjit Varki
Mar 11, 2008·Pulmonary Pharmacology & Therapeutics·Richard W Chapman
Mar 15, 2008·Pulmonary Pharmacology & Therapeutics·William M Abraham
Apr 24, 2008·Pulmonary Pharmacology & Therapeutics·Sandra Keir, Clive Page
Jun 10, 2008·Current Drug Targets·Fabio L M RicciardoloGert Folkerts
Jun 10, 2008·Current Drug Targets·Thomas TschernigReinhard Pabst
Jun 28, 2008·American Journal of Respiratory and Critical Care Medicine·Harm MaarsinghHerman Meurs
Nov 27, 2008·The Journal of Clinical Investigation·Virna Cortez-RetamozoMikael J Pittet
Jan 31, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B S Bochner
Feb 4, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P M O'ByrneJ D Brannan
Feb 12, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Steven M LeonardoStephen B Gauld
Mar 19, 2009·The Journal of Pharmacology and Experimental Therapeutics·Houari Korideck, Jeffrey D Peterson
Apr 28, 2009·Pulmonary Pharmacology & Therapeutics·Judith E AllenTara E Sutherland
Jun 30, 2009·American Journal of Physiology. Lung Cellular and Molecular Physiology·Jason H T BatesCharles G Irvin
Nov 3, 2009·Current Opinion in Chemical Biology·Scott A Hilderbrand, Ralph Weissleder
Dec 18, 2009·Endocrinology·Rodney F Minchin, Darren J Martin
Jul 22, 2010·Swiss Medical Weekly·Sébastien Conus, Hans-Uwe Simon
Jan 1, 2010·Journal of Asthma and Allergy·Simon G RoyceMimi L K Tang
Jun 3, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Ana Paula Moreira, Cory M Hogaboam
Jul 5, 2011·Drug Discovery Today·Anthony M HolmesStephen T Holgate
Feb 2, 2012·Journal of Leukocyte Biology·Ming YangPaul S Foster
Mar 14, 2012·The Journal of Allergy and Clinical Immunology·Stanley J SzeflerMichael Minnicozzi
May 5, 2012·Journal of Zhejiang University. Science. B·Yin-he Feng, Hui Mao
Aug 23, 2012·Mucosal Immunology·J Balhara, A S Gounni
Oct 11, 2012·Seminars in Respiratory and Critical Care Medicine·D Robin Taylor

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Citations

Oct 4, 2018·Drug Delivery and Translational Research·Durga M S H ChandrupatlaGerrit Jansen

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