Biomarkers of lipid peroxidation related to hypertension in aging

Hypertension Research : Official Journal of the Japanese Society of Hypertension
H YavuzerH Uzun

Abstract

The aim of this clinical study was to evaluate the influence of aging on the levels of lipid peroxidation (quantified as thiobarbituric acid-reactive substances (TBARS) content), lipid hydroperoxide (LOOH), hexanoyl lysine (HEL), 8-iso-prostaglandin F2α (8-iso-PGF2α) and total antioxidant capacity (TAC), and determine their relationships to the demographic and cardiovascular risk factors in elderly hypertensive (HT) patients. This study consisted of four groups: two elderly groups with 30 HT patients (11 males, 19 females) and 30 normotensive healthy volunteers (15 males, 15 females), and two young groups with 30 HT patients (13 males, 17 females) and 30 normotensive healthy volunteers (12 males, 18 females). In the elderly control group, the TBARS, LOOH, HEL and 8-iso-PGF2α levels, and the carotid intima media thickness (CIMT) were significantly higher than in the young control group. The TBARS, LOOH, HEL and 8-iso-PGF2α levels and the CIMT measurements were significantly higher in the elderly HT group than in the young HT group. In addition, the TAC levels were significantly lower in the elderly and young HT groups than in the elderly and young control groups. The CIMT was significantly positively correlated with TBARS (r=0.4...Continue Reading

References

Jan 1, 1978·Methods in Enzymology·J A Buege, S D Aust
May 19, 2000·Experimental Gerontology·P D ReavenJ L Witztumc
Jan 16, 2004·Experimental Gerontology·Ildiko SeresAbdelouahed Khalil
Feb 27, 2004·Journal of Human Hypertension·H UzunS Erdine
Oct 20, 2004·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Atsushi HozawaIchiro Tsuji
Jul 26, 2005·Clinical Chemistry·Bin WangRongbin Yu
Apr 7, 2007·American Journal of Therapeutics·María Cristina Armas-PadillaManuel Valasco
May 22, 2007·The Journal of Nutrition·Helmut Sies
Jun 26, 2007·American Journal of Hypertension·Norihisa ItoToshio Ogihara
Mar 18, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ramón RodrigoJean P Bächler
Mar 28, 2008·Journal of Pineal Research·Kornelia Kedziora-KornatowskaJózef Kedziora
Apr 7, 2010·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Samar Basu
Jul 3, 2010·Journal of the American College of Nutrition·Ligia J DominguezMario Barbagallo
Jun 3, 2011·Clinical and Investigative Medicine. Médecine Clinique Et Experimentale·Omur TabakHafize Uzun
Mar 1, 2007·Indian Journal of Clinical Biochemistry : IJCB·V Prashant AkilaBenedicta D'souza
Dec 4, 2013·Aging Clinical and Experimental Research·Ana Carla da CruzFelipe Dal-Pizzol
Mar 25, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Ana Paula Cabral de FariaHeitor Moreno
May 9, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Wuxiang XieDong Zhao
Aug 8, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Mohammad R Al-MagablehJoanne L Hart
Aug 12, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Per O IversenMarit B Veierød
Oct 11, 2014·Oxidative Medicine and Cellular Longevity·Kota V RamanaSharad S Singhal
Oct 17, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Sae Mi YooSang Hong Baek
Feb 11, 2015·European Journal of Nutrition·P Henríquez-SánchezL Serra-Majem
Apr 30, 2015·Journal of Diabetes and Metabolic Disorders·Stanley Ir OkoduwaNathan Habila

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Citations

Mar 27, 2019·Journal of Toxicology and Environmental Health. Part a·Carla Da Silva MachadoLusânia Maria Greggi Antunes
Sep 29, 2019·Aging Cell·Adiv A Johnson, Alexandra Stolzing
Oct 26, 2018·Physiological Reviews·Agustin Gonzalez-VicenteJeffrey L Garvin
Oct 28, 2019·Cardiovascular Endocrinology & Metabolism·Hesham AlharbySaeed Yafei
Oct 8, 2020·International Journal of Molecular Sciences·Marta KollarovaJana Radosinska
Oct 30, 2020·Bioscience of Microbiota, Food and Health·Eric Banan-Mwine DaliriDeog-Hwan Oh
Jul 3, 2020·Experimental Gerontology·Iván Cuyul-VásquezGabriel Nasri Marzuca-Nassr
Jun 15, 2021·Domestic Animal Endocrinology·F A C SoaresF H D González

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