Biomarkers of multiorgan injury in neonatal encephalopathy

Biomarkers in Medicine
Saima Aslam, Eleanor J Molloy

Abstract

Neonatal encephalopathy (NE) is a major contributor to neurodevelopmental deficits including cerebral palsy in term and near-term infants. The long-term neurodevelopmental outcome is difficult to predict with certainty in first few days of life. Multiorgan involvement is common but not part of the diagnostic criteria for NE. The most frequently involved organs are the heart, liver, kidneys and hematological system. Cerebral and organ involvement is associated with the release of organ specific biomarkers in cerebrospinal fluid, urine and blood. These biomarkers may have a role in the assessment of the severity of asphyxia and long-term outcome in neonates with NE.

References

Mar 1, 1992·Pediatric Neurology·A Leviton, K B Nelson
Apr 1, 1991·American Journal of Diseases of Children·E W NelsonP L McCarthy
May 1, 1986·The Journal of Pediatrics·V CastleC Carter
Nov 1, 1995·The Journal of Pediatrics·A Martín-AncelJ Quero
Dec 1, 1995·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M G Karlowicz, R D Adelman
Apr 12, 2000·Pediatric Research·A D Edwards, D V Azzopardi
Apr 30, 2002·Obstetrics and Gynecology·Gary D V HankinsGarland D Anderson
Oct 23, 2002·Brain : a Journal of Neurology·Heike J SchochHugo H Marti
Mar 29, 2003·European Journal of Clinical Investigation·C ChiesaL Pacifico
Apr 1, 2003·IUBMB Life·Aldrin V GomesDanuta Szczesna-Cordary
May 28, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·B GhoshV Dadhwal
Feb 24, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·P ShahM Perlman
Oct 22, 2004·Pediatric Research·Agnes I BarthaDonna M Ferriero
Mar 19, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·Hany AlyKantilal Patel
Sep 27, 2005·Brain & Development·Hany AlyBothina M Hasanein
Jun 16, 2006·Current Opinion in Nephrology and Hypertension·Kai M Schmidt-OttJonathan Barasch
Oct 26, 2006·Acta Paediatrica·Mathias KarlssonBirger Winbladh
Apr 20, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·A A MorkosD M Angeles
Jul 28, 2007·Acta Paediatrica·Karin B Nelson
Aug 4, 2007·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jeffrey P PhelanGilbert I Martin
Oct 14, 2008·Brain & Development·Shinpei SunagawaSusumu Furukawa
Oct 18, 2008·Brain & Development·Hany AlyWael Atiea
Feb 17, 2009·Pediatric Neurology·Vijay RamaswamyJerome Yager
May 16, 2009·Current Neurovascular Research·Distefano GiuseppeAmato Maurizio
Aug 27, 2009·Pediatrics·Deirdre M MurraySean Connolly
Oct 24, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael HaaseUNKNOWN NGAL Meta-analysis Investigator Group
Dec 29, 2009·Frontiers in Bioscience (Elite Edition)·Pasquale FlorioMirella Strambi
Feb 10, 2010·Pediatric Cardiology·Mohamed MatterMohamed Al-Arman
Nov 17, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Brankica VasiljevicDragana Lutovac
Feb 2, 2011·The Journal of Pediatrics·Mary E BaumanM Patricia Massicotte
Feb 22, 2011·Early Human Development·B H WalshD M Murray
May 18, 2011·Annals of Tropical Paediatrics·S KaurJ Kaur
Jun 10, 2011·Pediatric Research·Olaf DammannPierre Gressens
Jul 26, 2011·American Journal of Obstetrics and Gynecology·Christopher S EnnenErnest M Graham

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Citations

Jan 11, 2017·Scientific Reports·Ángel Sánchez-IllanaJulia Kuligowski
Nov 2, 2016·Pediatric Research·Håvard T GarbergOla Didrik Saugstad
Oct 7, 2020·Biomarkers in Medicine·Moises Rodriguez-GonzalezAna Castellano-Martinez

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