PMID: 26329414Sep 4, 2015Paper

Biomarkers of Orthodontic Tooth Movement in Gingival Crevicular Fluid: A Systematic Review

The Journal of Contemporary Dental Practice
Adel M Alhadlaq

Abstract

The analysis of gingival crevicular fluid (GCF) may be an acceptable way to examine the ongoing biochemical processes associated with bone turnover during orthodontic tooth movement. If it is possible to biologically monitor and predict the outcome of orthodontic forces, then the management of appliances could be based on individual tissue responses, and the effectiveness of the treatment could be improved. A literature search was carried out in major databases, such as medline, EMBASE, cochrane library, web of science, google scholar and scopus for relevant studies. Publications in English between 2000 and 2014 which estimated GCF markers as indicators of orthodontic tooth movement were included. The list of biomarkers available to date was compiled and presented in table format. Each biomarker is discussed separately based on the available evidence. Several sensitive GCF markers are available to detect the biomechanical changes occurring during orthodontic tooth movement. Further focused research might help to analyze the sensitivity and reliability of these indicators, which in turn can lead to the development of chairside tests to assess the outcome of orthodontic therapy.

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Citations

May 23, 2019·Dental press journal of orthodontics·Priyanka KapoorRajeswari Moganty
Nov 2, 2016·The Angle Orthodontist·Tommaso CastroflorioAndrea Deregibus
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Aug 7, 2021·Biomedicines·Christian KirschneckAgnes Schröder
Dec 9, 2021·European Journal of Orthodontics·Dimitrios KloukosChristos Katsaros

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