Biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis

Open Access Rheumatology : Research and Reviews
Rosario PelusoRaffaele Scarpa

Abstract

Background: Psoriatic arthritis (PsA) is a chronic immune-mediated disease. It is associated with an increase in cardiovascular risk factors (obesity, hypertension, diabetes, and dyslipidemia), giving a higher risk of major adverse cardiovascular events. Patients with PsA have an increased incidence of subclinical atherosclerosis and endothelial dysfunction. The aim of this study is to perform a review of the biomarkers of subclinical atherosclerosis in patients with PsA. Methods: A search was performed in the electronic databases (PubMed, Web of Science, Scopus, and Embase) up until July 2017. Studies were considered if they included data on biomarkers of subclinical atherosclerosis in PsA, and each article was then reviewed for quality and clinical relevance. After completing the literature search, all screened literature was summarized and discussed in our study group (CaRRDs study group). Results: The initial search produced 532 abstracts, which were limited to 258 potentially relevant articles by preliminary review of the titles and by excluding review articles and case reports (n=274). A further 102 articles were deemed ineligible after examining the abstracts. Full texts of the remaining 156 articles were retrieved. Most...Continue Reading

Citations

Mar 10, 2020·Expert Review of Clinical Immunology·Francesco CasoLuisa Costa
Oct 13, 2019·Rheumatology International·Francesco CasoLuisa Costa
Jul 27, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Gashaw DessieMeseret Derbew Molla

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