Biomechanical and morphological study of a new elastic mesh (Ciberlastic) to repair abdominal wall defects

Journal of the Mechanical Behavior of Biomedical Materials
B CalvoJuan Manuel Bellón

Abstract

The aim of this study was to conduct a preclinical evaluation of the behaviour of a new type of abdominal LW prosthesis (Ciberlastic), which was designed with a non-absorbable elastic polyurethane monofilament (Assuplus, Assut Europe, Italy) to allow greater adaptability to mechanical area requirements and higher bio-mimicking with the newly formed surrounding tissues. Our hypothesis was that an increase in the elasticity of the mesh filament could improve the benefits of LW prostheses. To verify our hypothesis, we compared the short- and long-term behaviour of Ciberlastic and Optilene(®) elastic commercial meshes by repairing the partially herniated abdomen in New Zealand White rabbits. The implanted meshes were mechanically and histologically assessed at 14 and 180 days post-implant. We mechanically characterized the partially herniated repaired muscle tissue and also determined mesh shrinkage at different post-implant times. This was followed by a histological study in which the tissue incorporation process was analysed over time. The new prosthesis designed by our group achieved good behaviour that was similar to that of Optilene(®), one of the most popular LW prostheses on the market, with the added advantage of its elasti...Continue Reading

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Citations

Sep 19, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jing QiaoBaoqin Han
Apr 16, 2021·ACS Biomaterials Science & Engineering·Zhengni LiuRui Tang

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