Biomechanical comparison of Thiel embalmed and fresh frozen nerve tissue

Anatomical Science International
Michael E J StouthandelTom Van Hoof

Abstract

The aim of this study was to determine the effect of Thiel embalming on the biomechanical properties of nerve tissue, to validate the use of Thiel embalmed bodies as a reliable model system for obtaining biomechanical data to supplement neurodynamic models, for anesthesiological and neurosurgical training and for future preclinical test set-ups involving nerve tissue. Upon the arrival of a body at the anatomy department, a fresh median nerve was harvested, the harvest site was sutured and following the Thiel embalming procedure the Thiel embalmed median nerve of the opposing wrist was harvested. Micro CT was performed to establish the cross-sectional area and biomechanical tensile testing was performed to compare the Young's modulus/elasticity of fresh frozen and Thiel embalmed nerves. Thiel embalming did not cause a significant difference in elasticity when comparing Thiel embalmed and fresh frozen specimens. A correlation was found between the cross-sectional area of Thiel embalmed nerve specimens and their Young's modulus. Thiel embalming does not significantly alter the elasticity of nerve tissue compared to fresh frozen nerve tissue. Similar shapes were observed when comparing the stress/strain curves of both specimen type...Continue Reading

References

Jun 1, 1992·Acta Orthopaedica Scandinavica·M K KwanS R Garfin
May 20, 2005·American Journal of Obstetrics and Gynecology·Kuo-Cheng LienJames A Ashton-Miller
Nov 16, 2005·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Stephen D Anderson
Nov 1, 2006·IEEE Transactions on Bio-medical Engineering·Pier Nicola SergiSilvestro Micera
Jun 7, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Tom Van HoofKatharina D'Herde
Jul 29, 2010·Surgical and Radiologic Anatomy : SRA·Mehdi BenkhadraGeorg Feigl
Apr 23, 2011·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Gion FesselJess G Snedeker
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Hans-Joachim WilkeTobias M Böckers
Feb 25, 2015·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Xiaochun LiaoZhihong Huang
Sep 18, 2015·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Matthias André VerstraeteJan Victor
Sep 28, 2016·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Michel P BonninJan Victor
Oct 5, 2016·Journal of Experimental Orthopaedics·Michel P BonninJan Victor
Jan 13, 2017·Journal of Brachial Plexus and Peripheral Nerve Injury·Andrei OdobescuMichel Alain Danino
Apr 16, 2017·Journal of the Mechanical Behavior of Biomedical Materials·Florian VöllnerMarkus Weber
Jun 8, 2018·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Erik HohmannAndreas Imhoff
Oct 3, 2018·The Journal of Craniofacial Surgery·Nazzar TellisiOuti Kaarela

❮ Previous
Next ❯

Citations

Nov 13, 2020·Frontiers in Bioengineering and Biotechnology·Benedetta E FornasariStefania Raimondo
Jun 7, 2021·Journal of Biomechanical Engineering·Virginia OrozcoAnita Singh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft
Gion FesselJess G Snedeker
The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
Roos EismaRoger W Soames
Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy
Ioannis KarakitsiosAndreas Melzer
Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Johann ZwirnerNiels Hammer
© 2021 Meta ULC. All rights reserved