Biomechanical evaluation of an autologous flexor digitorum lateralis graft to augment the surgical repair of gastrocnemius tendon laceration in a canine ex vivo model

Veterinary Surgery : VS
Daniel J DuffyGeorge E Moore

Abstract

To evaluate the effect of an autologous flexor digitorum lateralis (FDL) graft to augment a three-loop pulley (3LP) core repair in a canine cadaveric gastrocnemius tendon (GT) laceration model. Ex vivo, biomechanical study. Twenty-six canine cadaveric hind limbs. Tendons were divided into two groups (n = 13). After sharp transection, paired GT were repaired with 3LP or 3LP + FDL tendon augmentation. Yield, peak and failure loads, tensile loads required to create 1 and 3-mm gapping, and failure modes were analyzed. Significance was set at P < .05. Yield and failure force (mean ± SD) for 3LP + FDL were 134.9 ± 44.1 N and 205.4 ± 46.4 N, respectively, which were greater than for 3LP alone (67.9 ± 12.2 N and 91.8 ± 9.9 N, respectively, P < .0001). No constructs (0%) formed 1 or 3-mm gaps in the 3LP + FDL graft group compared with 84% and 39% for 3LP, respectively (P < .0001). Failure modes were different between groups (P < .001), with 85% of 3LP + FDL constructs failing by tissue rupture at the myotendinous junction, distant to the repair site. Addition of an autologous FDL graft to a core 3LP tendon repair increased yield, peak, and failure forces by twofold, 2.3-fold, and 2.2-fold, respectively, compared with core 3LP alone whil...Continue Reading

References

Nov 1, 1977·The Journal of Hand Surgery·G D ListerE Atasoy
Jul 1, 1991·The Journal of Hand Surgery·D L PruittB Fink
Jan 1, 1986·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R H GelbermanD Amiel
Oct 1, 1981·The Journal of Small Animal Practice·L C Vaughan
Jul 1, 1994·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G A MurrellT M Best
Aug 1, 1996·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·H KubotaP R Manske
Aug 5, 2000·Foot & Ankle International·S G PneumaticosS G Trevino
Nov 28, 2001·The Journal of Small Animal Practice·M KramerS Kindler
Apr 30, 2008·Foot & Ankle International·Bryan D Den Hartog
Sep 15, 2009·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·J NortonR Rooks
Feb 13, 2010·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·P J GilbertB Singh
Sep 14, 2010·The Veterinary Record·S A CorrD Brodbelt
Jan 13, 2011·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·R L MeesonG I Arthurs
Jun 27, 2015·Veterinary Surgery : VS·Mark A MortonJohn F Innes
Nov 17, 2016·BioMed Research International·Yangjing LinXiaojun Duan
Mar 17, 2017·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Matteo GuzziniAndrea Ferretti
Feb 3, 2018·Veterinary Surgery : VS·Eric M ZellnerKarl H Kraus

❮ Previous
Next ❯

Citations

Jun 3, 2021·Veterinary Surgery : VS·Michael J HaleKarl H Kraus
Jun 12, 2021·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·Alessandro Boero BaroncelliLisa Adele Piras

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.