Biomechanical implant fixation of CoCrMo coating inferior to titanium coating in a canine implant model

Journal of Biomedical Materials Research. Part a
Stig S JakobsenKjeld Soballe

Abstract

The use of CoCrMo in orthopedic surgery is not new, and CoCrMo (cobalt-chromium-molybdenum) is well tolerated. Nevertheless, the alloy is still considered less biocompatible than titanium. We therefore wanted to explore the biocompatibility of CoCrMo by investigating the biomechanical implant fixation and implant osseointegration of CoCrMo (ASTM F-75) porous bead-coated and titanium (ASTM F-136) porous bead-coated implants. In 10 dogs, the two implant types were inserted into the proximal part of the humerus. Implant sites were overdrilled, leaving an empty 0.75-mm gap between implant and surrounding bone. The implants were observed for 6 weeks and were evaluated by biomechanical push-out test and histomorphometry. We found a statistically significant 40% decrease in the biomechanical fixation of CoCrMo porous bead-coated implants compared with titanium porous bead-coated implants. Implant osseointegration was comparable between the two implants; however, a slight decrease in bone volume density around CoCrMo implants was observed. Insertions of CoCrMo implants are associated with a disturbance of the delicate peri-implant milieu. Even from implants not subjected to any mechanical forces, metal ions are liberated and result in ...Continue Reading

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Citations

Sep 15, 2012·Journal of Neuroscience Methods·S A HackingE P Cook
Oct 31, 2019·Journal of Biomedical Materials Research. Part a·Yu LiuJörg Eschweiler
Mar 1, 2019·Tissue Engineering and Regenerative Medicine·Seung Chan KimYoung Wook Lim
Mar 26, 2016·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Richard RodaPaul E Beaulé
Feb 11, 2018·Journal of Biomedical Materials Research. Part a·Furqan A ShahAnders Palmquist
Nov 9, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Amir A Zadpoor

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