Biomechanical properties of lumbar endplates and their correlation with MRI findings of lumbar degeneration

Journal of Biomechanics
Junhui LiuFengdong Zhao

Abstract

How stiffness and strength of the human lumbar endplate vary with location, spinal level, and its correlation with MRI findings of lumbar degeneration, has not been reported in detail. 27 lumbar spines (16 male, 11 female, 31-49yrs) were harvested from cadavers without history of lumbar lesion or trauma. Disc and endplate degeneration was evaluated from MRI. Micro-CT was used to evaluate endplate microstructure. Indentation tests were performed to quantify stiffness and strength at 23 sites on each endplate from load-displacement graphs. Results showed that stiffness and strength increased from the centre of the endplate towards its periphery. There was no general age-related reduction in endplate stiffness or strength, although strength decreased slightly with age opposite the inner annulus. Disc degeneration was associated with a 39-46% decrease in stiffness, and a 21-30% decrease in strength, with effects being greatest near the endplate periphery. The presence of Modic changes had a similar effect. Strength and stiffness consistently increased at lower spinal levels, and were consistently greater in the inferior endplate (relative to the vertebra). Gender had little influence, although stiffness in the peripheral endplate w...Continue Reading

References

Jul 1, 1988·Radiology·M T ModicJ R Carter
Sep 1, 1987·AJR. American Journal of Roentgenology·A de RoosM Dalinka
Nov 1, 1987·Clinical Orthopaedics and Related Research·L T Twomey, J R Taylor
Nov 1, 1996·The Journal of Bone and Joint Surgery. British Volume·M A AdamsP Dolan
Jun 18, 1998·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·B JostL P Nolte
Dec 5, 1998·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·I BraithwaiteB A Taylor
Jul 15, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T HildebrandP Rüegsegger
Oct 18, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J P GrantCharles G Fisher
Jan 7, 2004·Journal of Biomechanics·P PollintineM A Adams
Jan 22, 2004·Journal of Spinal Disorders & Techniques·Sten HolmTommy Hansson
Mar 3, 2007·Journal of Neurosurgery. Spine·Michael T Modic
Mar 6, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hanne B Albert, Claus Manniche
Mar 14, 2007·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Felix EcksteinEva-Maria Lochmüller
Dec 20, 2007·Spine·Daniel SkrzypiecMichael A Adams
Mar 19, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Baogan PengXinyu Zhang
Jun 13, 2012·Journal of Anatomy·Girish PattappaSibylle Grad
Feb 12, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hanne B AlbertTom Elliott
Jul 17, 2015·Microscopy Research and Technique·Liu JunhuiZhao Fengdong

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Citations

Jan 22, 2017·The Spine Journal : Official Journal of the North American Spine Society·Uruj ZehraPatricia Dolan
May 6, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Richard BostelmannMartin Barth
Jul 27, 2021·Journal of Magnetic Resonance Imaging : JMRI·Rahman Ud DinHaisheng Yang

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