Biomechanical properties of vaginal tissue: preliminary results

International Urogynecology Journal and Pelvic Floor Dysfunction
Chrystèle RubodMichel Cosson

Abstract

The aim of this study is to characterise the biomechanical properties of vaginal tissue to develop an accurate cure of pelvic organ prolapse (POP). Prolapsed vaginal tissues were extracted during the prolapse cure of five patients (POP) and on five cadavers without noticed pelvic floor dysfunction (non-pelvic organ prolapse) with agreement of the ethics committee. Uni-axial tension was performed, and the results were analysed. Individual reproducibility of experimental results was good, and the results highlight the non-linear relationship between stress (force per unit of surface) and strain (l-l(0)/l(0)) and very large deformation before rupture appearance. This experimental study has proven for the first time that the mechanical behaviour of vaginal tissue has to be defined as hyperelastic with a large deformation. This response has to be taken into account to develop accurate synthetic prostheses for POP cure and in the numerical simulation of the pelvic floor.

References

Apr 1, 1997·Obstetrics and Gynecology·A L OlsenA L Clark
Sep 5, 1998·Medical Engineering & Physics·G J EttemaM R Forwood
Feb 13, 1999·American Journal of Obstetrics and Gynecology·E C SamuelssonK F Svärdsudd
Jun 11, 2002·International Urogynecology Journal and Pelvic Floor Dysfunction·J T W Goh
Sep 23, 2003·Current Opinion in Obstetrics & Gynecology·Judith T W Goh
Jan 30, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Michel CossonAnne Ego
Oct 7, 2006·International Urogynecology Journal and Pelvic Floor Dysfunction·Lingling LeiRiQi Chen
May 15, 2007·The Journal of Urology·Chrystèle RubodMichel Cosson

❮ Previous
Next ❯

Citations

Sep 3, 2008·International Urogynecology Journal and Pelvic Floor Dysfunction·Hannah KrauseJudith Goh
May 5, 2010·International Urogynecology Journal·Yvonne HsuJohn O L DeLancey
Sep 15, 2010·International Urogynecology Journal·Clay Jean-CharlesMichel Cosson
Sep 15, 2010·International Urogynecology Journal·Marie BoennelyckeGunnar Lose
Apr 5, 2011·International Urogynecology Journal·Pedro A L S MartinsAntónio J M Ferreira
Jun 19, 2012·International Urogynecology Journal·Michel CossonM Brieu
Dec 5, 2012·International Urogynecology Journal·Andrew FeolaSteven Abramowitch
Sep 25, 2012·Archives of Gynecology and Obstetrics·Pedro MartinsAntónio M Ferreira
May 7, 2009·Biomechanics and Modeling in Mechanobiology·Estefania PeñaM Doblaré
Feb 11, 2010·Computer Methods in Biomechanics and Biomedical Engineering·P MartinsA Ferreira
Jul 14, 2009·Current Opinion in Obstetrics & Gynecology·Hannah G Krause, Judith Tw Goh
Mar 12, 2010·Archives of Gynecology and Obstetrics·Agnaldo Lopes da Silva-FilhoRenato M Natal Jorge
Aug 28, 2010·International Urogynecology Journal·Boris GabrielMichel Cosson
Nov 11, 2011·International Urogynecology Journal·Vladimir EgorovVincent Lucente
Nov 30, 2015·Journal of the Mechanical Behavior of Biomedical Materials·S TodrosA N Natali
Jan 17, 2012·Urology·Chrystèle RubodBoris Gabriel
Mar 17, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Steven D AbramowitchPamela A Moalli
Dec 15, 2015·International Urogynecology Journal·Laurent de LandsheereMichel Cosson
Oct 21, 2015·Journal of the Mechanical Behavior of Biomedical Materials·Mathias BrieuMichel Cosson
Dec 21, 2010·Journal of Biomedical Materials Research. Part a·Ignacio OchoaManuel Doblaré
Jun 15, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·Y OzogJ Deprest
Jan 24, 2009·Journal of Biomechanics·B CalvoA Ferreira
Apr 29, 2015·Journal of the Mechanical Behavior of Biomedical Materials·Edoardo Mazza, Alexander E Ehret
Sep 10, 2014·Journal of the Mechanical Behavior of Biomedical Materials·M M MaurerE Mazza
Sep 4, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Alexandros DerpapasVik Khullar
Oct 16, 2014·International Urogynecology Journal·Sandra Ochoa LopezCheng-Jen Chuong
Dec 18, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Cheng-Jen ChuongPhilippe Zimmern
Apr 13, 2012·Computer Methods in Biomechanics and Biomedical Engineering·Clare YipGeoffrey Cundiff
May 14, 2016·Computer Methods in Biomechanics and Biomedical Engineering·Zhuo YangIan R Grosse
Sep 3, 2016·Journal of the Mechanical Behavior of Biomedical Materials·A MorchC Rubod
Aug 12, 2017·Neurourology and Urodynamics·Mahshid VashaghianJan-Paul Roovers
Dec 15, 2010·Gynecologic and Obstetric Investigation·Pedro A L S MartinsAgnaldo L Silva-Filho
Nov 25, 2017·Scientific Reports·Barbara RöhrnbauerDavid Amos Scheiner
Mar 21, 2013·Nature Materials·Kurt M Schmoller, Andreas R Bausch
Jul 12, 2018·Menopause : the Journal of the North American Menopause Society·Petra KochováZbyněk Tonar
Jan 8, 2019·Journal of Biomechanical Engineering·Jeffrey McGuireRaffaella De Vita
Dec 9, 2010·Nature Communications·K M SchmollerA R Bausch
Jan 26, 2010·Computer Methods in Biomechanics and Biomedical Engineering·G Venugopala RaoMichel Cosson
Sep 13, 2019·Menopause : the Journal of the North American Menopause Society·Petra KochováVladimir Kalis
Jul 3, 2019·Interface Focus·Jeffrey A McGuireRaffaella De Vita

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Urogynecology Journal and Pelvic Floor Dysfunction
Judith Goh
International Urogynecology Journal and Pelvic Floor Dysfunction
Lingling LeiRiQi Chen
Computer Methods in Biomechanics and Biomedical Engineering
G Venugopala RaoMichel Cosson
© 2021 Meta ULC. All rights reserved