Biomechanics and histology of bovine claw suspensory tissue in early acute laminitis

Journal of Dairy Science
A M DanscherO Wattle

Abstract

Weakening of the suspensory tissue supporting the pedal bone is the central issue in the theory of acute bovine laminitis, but this aspect has never been tested. The objective of this study was to investigate the effect of laminitis on the suspensory tissue. The hypothesis was that clinical and histological signs of acute laminitis are associated with decreased strength of the suspensory tissue of the bovine claw. Nonpregnant dairy heifers (n=10) received oral oligofructose overload (17 g/kg of body weight) and were killed 24 (n=4) and 72h (n=6) after overload. Control heifers (n=6) received tap water and were killed at 72 or 96h. Clinical, orthopedic, and histological examinations were carried out to confirm the occurrence of laminitis. After euthanasia, 2 adjacent tissue samples including the horn wall, lamellar layer, dermis, and pedal bone were cut from the dorso-abaxial aspect of each claw. Tissue samples were kept on ice until mounted on a mechanical testing frame, fixed by horn and bone, and loaded to failure. A stress displacement curve was generated and measurements of physiological support (force needed to displace 1mm beyond first resistance) and maximal support (force needed to break the tissue) were recorded. Heife...Continue Reading

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Citations

Aug 14, 2012·The Veterinary Journal·Trine H TølbøllEmøke Bendixen
Aug 9, 2012·The Veterinary Journal·J N Huxley
Jul 28, 2012·Proteomics·Stine L BislevMarius C Codrea
Jul 24, 2015·BMC Veterinary Research·Shu-Wei DongZhi-Qiang Yang
Nov 21, 2017·Journal of Dairy Science·A J HeinrichsC M Jones
Mar 8, 2020·Animals : an Open Access Journal From MDPI·Rejane Dos Santos SousaEnrico Lippi Ortolani
Aug 9, 2020·Frontiers in Veterinary Science·Jiafeng DingHongbin Wang
Nov 19, 2020·Animals : an Open Access Journal From MDPI·Carolina ManosalvaRafael Agustín Burgos
Jan 5, 2021·Frontiers in Veterinary Science·Shuaichen LiNa Zhang

Related Concepts

Oligofructose
Bos indicus
Cattle Diseases
Foot Diseases
Hoof
Oligosaccharides
Rietveld Refinement
Acidosis
Chromatin
Claw

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