Biomedical microelectromechanical systems (BioMEMS): Revolution in drug delivery and analytical techniques

Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society
Rishad R JivaniBhagyesh P Jhala

Abstract

Advancement in microelectromechanical system has facilitated the microfabrication of polymeric substrates and the development of the novel class of controlled drug delivery devices. These vehicles have specifically tailored three dimensional physical and chemical features which together, provide the capacity to target cell, stimulate unidirectional controlled release of therapeutics and augment permeation across the barriers. Apart from drug delivery devices microfabrication technology's offer exciting prospects to generate biomimetic gastrointestinal tract models. BioMEMS are capable of analysing biochemical liquid sample like solution of metabolites, macromolecules, proteins, nucleic acid, cells and viruses. This review summarized multidisciplinary application of biomedical microelectromechanical systems in drug delivery and its potential in analytical procedures.

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Feb 16, 2017·The Analyst·Meltem ElitaşHikmet Budak
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Methods Mentioned

BETA
electrophoresis
chip
biosensor
biosensors
chips
nucleic acid amplification
PCR
genotyping
fluorescence microscopy

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