Biomedical Potential of mTOR Modulation by Nanoparticles

Trends in Biotechnology
Laura HuleaVladimir Trajkovic

Abstract

Modulation of the mammalian target of rapamycin (mTOR), the principal regulator of cellular homeostasis, underlies the biological effects of engineered nanoparticles, including regulation of cell death/survival and metabolic responses. Understanding the mechanisms and biological actions of nanoparticle-mediated mTOR modulation may help in developing safe and efficient nanotherapeutics to fight human disease.

References

Nov 15, 2014·International Journal of Nanomedicine·Junchao DuanZhiwei Sun
Feb 6, 2015·The Journal of Clinical Investigation·Young Chul Kim, Kun-Liang Guan

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Citations

Oct 25, 2016·Trends in Biotechnology·Mahadevappa HemshekharKesturu S Girish
Jan 4, 2019·Advanced Healthcare Materials·Joshua M Gammon, Christopher M Jewell
Aug 22, 2020·International Journal of Nanomedicine·Mee-Sup Yoon
Jul 30, 2019·Small Methods·Weijun WeiWeibo Cai
Nov 22, 2019·Nanomedicine : Nanotechnology, Biology, and Medicine·Frantiescoli Anversa DimerClaus-Michael Lehr
Aug 30, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Adam FrtúsOleg Lunov

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