Biometric and refractive errors evaluation in patients with neurofibromatosis type 1.

European Journal of Ophthalmology
Aldo VaggeCarlo Enrico Traverso

Abstract

To analyze biometric changes and prevalence of refractive in patients with neurofibromatosis type 1 (NF1). Retrospective, case-controlled study involving patients affected by NF1 and healthy control subjects. Data on biometric measurements such as axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), keratometry (K1 and K2) values, and white-to-white (WTW), obtained by use of optical low-coherence reflectometry on a Lenstar LS 900® (Haag-Streit AG, Switzerland) were collected and analyzed. Cycloplegic refractions were then performed. Overall, 166 eyes of 83 patients diagnosed with NF1 (mean age 21.6 ± 9.8) were enrolled and compared with 178 eyes of age-matched healthy subjects (mean age 22.6 ± 6.6). One hundred sixty-six (22.8%) and 33 of 178 (18.5%) eyes were myopic in NF1 patients and healthy subjects, respectively. The prevalence of hyperopia in the NF1 group was 12 of 166 (7.2%) whereas in the healthy control group was 14 of 178 (8.9%). Twenty-nine of 166 (17.4%) and 34 of 178 (19.1%) eyes presented astigmatism in NF1 and control group, respectively. These differences were not statistically significant (p-values > 0.05). Refractive errors such as myopia, hyperopia, and astig...Continue Reading

References

Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A H Weiss, E A Ross
Jul 2, 1997·JAMA : the Journal of the American Medical Association·D H GutmannD Viskochil
Feb 24, 2001·International Ophthalmology Clinics·K C Sippel
Jul 26, 2003·The British Journal of Ophthalmology·A H Weiss
Aug 13, 2003·Archives of Ophthalmology·Robert N KleinsteinUNKNOWN Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error Study Group
Jan 5, 2007·The British Journal of Ophthalmology·Arsen AkinciAydan Degerliyurt
Jul 23, 2008·Ophthalmic Plastic and Reconstructive Surgery·Jern Y ChenScott D Brown
Apr 28, 2009·European Journal of Ophthalmology·Aylin ArdagilAyse Dolar
Sep 5, 2009·Ophthalmology·Jose MoralesThomas M Bosley
Mar 1, 2012·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Alejandra G de Alba CampomanesGrant T Liu
Mar 25, 2014·Journal of Child Neurology·Gad DotanAnat Kesler
Jun 14, 2014·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Gad DotanAnat Kesler
Jul 18, 2014·Lancet Neurology·Angela C Hirbe, David H Gutmann
Oct 30, 2016·European Journal of Ophthalmology·Necati DuruEmin Özlü
Sep 17, 2016·Journal of Pediatric Ophthalmology and Strabismus·Aldo VaggeCarlo Enrico Traverso
Oct 31, 2017·Survey of Ophthalmology·Michael KinoriJanice Lasky Zeid
Jan 1, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Antonietta MoramarcoAlessandro Lambiase
Sep 15, 2018·Clinical Ophthalmology·Christos TheophanousDonald S Fong

❮ Previous
Next ❯

Software Mentioned

GraphPad
Prism

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Epidemiology
S A Rasmussen, Jan M Friedman
European Journal of Pediatrics
Binnaz CelikHatice Gamze Poyrazoglu
Translational Research : the Journal of Laboratory and Clinical Medicine
Rebekah TritzBrian K Stansfield
Archives of Disease in Childhood
C M Beadle
© 2022 Meta ULC. All rights reserved