Biomonitoring of blood heavy metals and reproductive hormone level related to low semen quality

Journal of Hazardous Materials
Ching-Jen LiLing-Chu Chien

Abstract

Reproductive hormones and exposure to environmental metals are correlated with low-quality semen. The aim of this study was to evaluate the levels of heavy metals and reproductive hormones in the blood in addition to other relevant factors to clarify the relationship between these factors and semen quality. We recruited 154 male participants from a reproductive medical center. All participants were provided with a questionnaire on lifestyle implementation. The levels of metals in the blood were determined using inductively coupled plasma-mass spectrometry. The levels of hormones in the blood were determined using an automatic gamma counter. Multiple logistic regression analyses were conducted to predict the effects of statistically significant risk factors on semen quality by adjusting for relevant confounders and modifiers. After adjusting for the age, education level, and related factors in the multiple logistic regression analyses, we observed that the increased blood Pb levels were significantly and positively associated with low semen quality. High blood Pb levels (>50 μg/L) had an 11-fold risk of low semen quality. Our results suggest that progressive motility sperm may be a sensitive indicator of the semen quality among ...Continue Reading

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Citations

Dec 8, 2017·Critical Reviews in Clinical Laboratory Sciences·Prasenjit MitraPraveen Sharma
May 12, 2019·Environmental Science and Pollution Research International·Chin-En AiLing-Chu Chien
Sep 4, 2019·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Tugstênio L SouzaClaudia F Ortolani-Machado
Mar 2, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Xiao ShiTin-Chiu Li

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