Biophysical changes after mechanical injury of the stratum corneum in normal skin

Contact Dermatitis
Chang Hun HuhHee Chul Eun

Abstract

Scrubbing off the stratum corneum with a rough towel after soaking in warm water is a bathing custom unique to Korea. However, Korean dermatologists have advised against this practice due to the potential harm that it may cause, though there is little data to support this advice. This study aimed to evaluate the changes in biophysical characteristics after such mechanical injury of stratum corneum, as reflected by water-holding capacity, stratum corneum barrier function, and stratum corneum turnover time (SCTT). 10 Korean female volunteers (aged 19-34 years) were enrolled in this study to investigate the acute effects and 32 volunteers (aged 19-49 years) the chronic effects. After soaking in warm water (36 degrees C) for 5 min, the flexor surfaces of the forearms were scrubbed with a rough towel. The volunteers' forearms were divided into 4 compartments, and each compartment was scrubbed 0, 5, 10, and 15x, respectively. After a single injury of the stratum corneum, there was an initial decrease in water-holding capacity until 6 h. Thereafter, it increased until day (D) 3, when it began to descend to the normal range. The transepidermal water loss (TEWL) values also peaked at D2 and declined thereafter. However, there were no ch...Continue Reading

References

Oct 1, 1990·The Journal of Investigative Dermatology·D BommannanR H Guy
Jan 1, 1985·American Journal of Industrial Medicine·R Marks, D Black
Feb 1, 1974·The Journal of Investigative Dermatology·I C Mackenzie
Jan 1, 1983·Archives of Dermatological Research·S LeeJ S Kang
Apr 1, 1994·Journal of the American Academy of Dermatology·B J Nickoloff, Y Naidu
Nov 1, 1993·The British Journal of Dermatology·C J GravesR Marks
Apr 17, 2001·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S J BashirH I Maibach

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Citations

Jan 18, 2008·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·David Voegeli
Jan 24, 2008·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S H LimY B Choe
May 12, 2010·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Marty O VisscherRandy Wickett
Oct 15, 2013·International Journal of Older People Nursing·Fiona Cowdell, Katerina Steventon
Jun 9, 2016·International Journal of Nursing Studies·Jan Kottner, Christian Surber
Apr 11, 2008·British Journal of Nursing : BJN·David Voegell
Jul 8, 2010·British Journal of Nursing : BJN·David Voegeli
Jan 1, 2022·The Journal of Dermatology·Hidehisa SaekiAtsuyuki Igarashi

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