BiopLib and BiopTools-a C programming library and toolset for manipulating protein structure

Bioinformatics
Craig T Porter, Andrew C R Martin

Abstract

We describe BiopLib, a mature C programming library for manipulating protein structure, and BiopTools, a set of command-line tools which exploit BiopLib. The library also provides a small number of functions for handling protein sequence and general purpose programming and mathematics. BiopLib transparently handles PDBML (XML) format and standard PDB files. BiopTools provides facilities ranging from renumbering atoms and residues to calculation of solvent accessibility. BiopLib and BiopTools are implemented in standard ANSI C. The core of the BiopLib library is a reliable PDB parser that handles alternate occupancies and deals with compressed PDB files and PDBML files automatically. The library is designed to be as flexible as possible, allowing users to handle PDB data as a simple list of atoms, or in a structured form using chains, residues and atoms. Many of the BiopTools command-line tools act as filters, taking a PDB (or PDBML) file as input and producing a PDB (or PDBML) file as output. All code is open source and documented using Doxygen. It is provided under the GNU Public Licence and is available from the authors' web site or from GitHub. andrew@bioinf.org.uk.

References

May 29, 2000·Trends in Genetics : TIG·P RiceA Bleasby
Oct 27, 2010·BMC Bioinformatics·Andreas HildebrandtOliver Kohlbacher
May 2, 2013·Acta Crystallographica. Section D, Biological Crystallography·M BiasiniT Schwede
Nov 22, 2014·Bioinformatics·Layla HirshSilvio C E Tosatto

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Citations

Feb 12, 2020·Bioinformatics·Sam M Ireland, Andrew C R Martin

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Methods Mentioned

BETA
protein folding

Software Mentioned

Open Protein Simulator
Protein Library
BioPython
MinGW
BiopLib
GCC
Doxygen
BioPerl
ProFit
libxml2

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