Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites

Mycology
Rufin Marie Kouipou Toghueo

Abstract

Endophytic fungi became an attractive source for the discovery of new leads, because of the complexity and the structural diversity of their secondary metabolites. The genus Fusarium comprising about 70 species is extremely variable in terms of genetics, biology, ecology, and consequently, secondary metabolism and have been isolated from countless plants genera from diverse habitats. These endophytic microbes may provide protection and survival strategies in their host plants with production of a repertoire of chemically diverse and structurally unprecedented secondary metabolites reported to exhibit an incredible array of biological activities including antimicrobial, anticancer, antiviral, antioxidants, antiparasitics, immunosuppressants, immunomodulatory, antithrombotic, and biocontrol ability against plants pathogens and nematodes. This review comprehensively highlights over the period 1981-2019, the bioactive potential of metabolites produced by endophytes from Fusarium genus. Abbreviations: AIDS: Acquired immune deficiency syndrome; BAPT: C-13 phenylpropanoid side chain-CoA acyltransferase; CaBr2: Calcium bromide; DBAT: 10-deacetylbaccatin III-10-O-acetyl transferase; DNA: Deoxyribonucleic acid; EI-MS: Electron ionization...Continue Reading

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Citations

Jul 8, 2020·Critical Reviews in Biotechnology·Shu-Lei JiaZhen-Ming Chi
Jun 6, 2020·Frontiers in Bioengineering and Biotechnology·Ayomide Emmanuel Fadiji, Olubukola Oluranti Babalola
Sep 30, 2019·Natural Products and Bioprospecting·Rufin Marie Kouipou Toghueo
Dec 10, 2020·Microorganisms·Madira Coutlyne Manganyi, Collins Njie Ateba
Mar 7, 2021·Journal of Fungi·Bartholomew Saanu Adeleke, Olubukola Oluranti Babalola
Apr 20, 2021·Heliyon·Esraa Ahmed Mohamed El-BondklyAya Ahmed Mohamed El-Bondkly
Jun 18, 2021·Biological Reviews of the Cambridge Philosophical Society·Prasun KumarJintae Lee
Jul 3, 2021·Journal of Basic and Clinical Physiology and Pharmacology·Kartika Dyah PalupiAndria Agusta

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Methods Mentioned

BETA
MDA

Software Mentioned

OSMAC ( One Strain Many Compounds )

Related Concepts