Bioprosthetic valve failure. Comparative trial of two balloon-expandable transcatheter heart valve systems in intermediate-risk patients: a propensity score analysis.

Acta Cardiologica
Guering Eid-LidtJorge Gaspar

Abstract

The comparative mid and long-term durability, including the rates of bioprosthetic valve failure (BVF) of the Sapien XT® and Sapien 3® transcatheter heart valve (THV) in patients with intermediate surgical risk has not been reported. Consecutive intermediate-risk patients with severe aortic stenosis from the Mexican registry of transcatheter aortic valve replacement (TAVR) with Sapien® THVs were included. The primary endpoint was to compare the BVF rate between THVs at 2 years of follow-up. Secondary endpoints were comparisons of the composite of global mortality, cardiovascular mortality, and neurological events at 30 d and 24 months of follow-up. During 2014-2019, 115 (60 Sapien XT® and 55 Sapien 3®) patients met the inclusion criteria in five medical centres. The mean age was 77.3 ± 8.4 years. The average Society of Thoracic Surgeons Predicted Risk of Mortality (STS-PROM) was 5.6 ± 2.9. There was no statistically significant difference between the groups in BVF rate. At 30 d, overall, cardiovascular and non-cardiovascular mortality was 4.3%, 2.6%, and 1.7%, respectively. Neurological events rate was 1.73%. The mean long-term follow-up was 25.3 ± 14.2 months with an overall mortality of 9.56% but lower for the Sapien 3® group...Continue Reading

References

Dec 20, 2011·Journal of the American College of Cardiology·Ignacio J Amat-SantosEric Dumont
Oct 23, 2012·The Journal of Thoracic and Cardiovascular Surgery·A Pieter KappeteinUNKNOWN Valve Academic Research Consortium-2
Aug 19, 2014·The American Journal of Cardiology·Ignacio J Amat-SantosJosep Rodés-Cabau
Mar 20, 2015·Journal of the American College of Cardiology·Thomas WaltherUNKNOWN GARY Executive Board
Apr 16, 2015·Circulation. Cardiovascular Interventions·Azeem LatibAntonio Colombo
Feb 13, 2016·Journal of the American College of Cardiology·Maria Del TrigoJosep Rodés-Cabau
Mar 26, 2016·Journal of the American College of Cardiology·Torsten P VahlMartin B Leon
Apr 5, 2016·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER 2 Investigators
Nov 5, 2016·Journal of the American College of Cardiology·Nicolaj C HanssonBjarne L Nørgaard
Sep 14, 2016·JAMA : the Journal of the American Medical Association·Ander RegueiroJosep Rodés-Cabau
Mar 18, 2017·The New England Journal of Medicine·Michael J ReardonUNKNOWN SURTAVI Investigators
Aug 19, 2017·Journal of the American College of Cardiology·Tania Rodriguez-GabellaJosep Rodés-Cabau
Sep 25, 2017·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Marco BarbantiCorrado Tamburino
Dec 14, 2017·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Hashrul N RashidAdam J Brown
Oct 27, 2018·Journal of the American College of Cardiology·Andras P DurkoArie Pieter Kappetein
Apr 6, 2019·Journal of the American College of Cardiology·Jawad H ButtEmil L Fosbøl
Sep 10, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Tobias RheudeMichael Joner
Jan 30, 2020·The New England Journal of Medicine·Raj R MakkarUNKNOWN PARTNER 2 Investigators

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