PMID: 6404863Jan 1, 1983Paper

Biopsy and definitive radiation therapy in stages I and II carcinoma of the female breast

International Journal of Radiation Oncology, Biology, Physics
G R RayM Gribble

Abstract

One hundred-twenty patients with Stages I and II carcinoma of the female breast were treated by biopsy followed by definitive radiation therapy without mastectomy. The breast received 4500-5000 cGy (rad) using a 6 MV linear accelerator followed by a supplement to the area of the primary tumor of 2000 cGy (rad) using electrons in 99 patients (83%) and interstitial implantation in 21 patients (17%). Local recurrence was not recorded in the 43 patients with Stage I disease, while three of 77 patients (4%) with Stage II disease suffered a local recurrence. The actuarial five-year relapse-free survival was 91% and 60% in Stages I and II respectively. Cosmetic results were considered excellent by both physician and patient in the majority of cases. Axillary dissection was the recommended method of staging the axilla but was noted to be more morbid than axillary sampling. Electrons may be as effective as interstitial implantation as a means of supplementation following external beam therapy if specific guidelines are followed.

References

Oct 1, 1978·American Journal of Surgery·S Kaufman, J M Loré
Jan 1, 1980·International Journal of Radiation Oncology, Biology, Physics·A M ChuG Rodkey
Jan 1, 1980·International Journal of Radiation Oncology, Biology, Physics·B PierquinS Hannoun
Jan 1, 1981·The New England Journal of Medicine·G Bonadonna, P Valagussa

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Citations

Jul 1, 1991·International Journal of Radiation Oncology, Biology, Physics·J R GrayJ Yahalom
Jan 1, 1994·International Journal of Radiation Oncology, Biology, Physics·G R RayI Macio
Aug 1, 1984·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J R Yarnold
Jul 1, 1986·General Hospital Psychiatry·L BaiderA K De-Nour
Nov 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A M MoodyJ R Yarnold
Jun 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·D ZierhutM Wannenmacher
Feb 8, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Christy GoldsmithUNKNOWN FAST Trialists' Group
Jan 24, 1998·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Y Danjo
Nov 22, 2007·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·E M Messmer
Jan 22, 2003·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·J FarrellR D Sturrock

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