PMID: 8166527Apr 1, 1994Paper

Biopsy-induced tricuspid regurgitation after cardiac transplantation

The Annals of Thoracic Surgery
C B HuddlestonM K Pasque

Abstract

Transvenous endomyocardial biopsy is now well-established as the gold standard for evaluation of possible rejection episodes after cardiac transplantation. From 1985 to August 1992, 1990 patients have undergone 193 cardiac transplantations at Barnes Hospital. One hundred eighty-three patients survived their initial hospitalization and serve as the study group. Their records were reviewed for the purposes of identifying those with tricuspid regurgitation as a complication of right ventricular endomyocardial biopsy. These patients have undergone a total of 2,960 biopsies for an average of 16.2 biopsies per patient. Over a mean follow-up period of 4.22 years, all patients have been evaluated with standard two-dimensional echocardiograms. Mild to moderate tricuspid regurgitation was very common, but was thought to be biopsy-induced only if severe and accompanied by flail components of the tricuspid valve. Twelve patients were identified with this entity at our institution. Of these, 5 had no symptoms and were receiving no diuretics, 3 had mild symptoms consisting of lower extremity edema and continued to receive diuretics, 2 had moderate symptoms, and 2 had right heart failure and anasarca refractory to medical therapy. Both of the...Continue Reading

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Citations

Feb 1, 1995·The Annals of Thoracic Surgery·R D StahlD G Renlund
Feb 1, 1996·The Annals of Thoracic Surgery·M W WestonN S Sastry
Sep 1, 1995·The Annals of Thoracic Surgery·M di SummaS Marra
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