Biopsy of musculoskeletal tumours--beware

ANZ Journal of Surgery
Robin C Pollock, Paul D Stalley

Abstract

Biopsy of musculoskeletal tumours is hazardous and, when poorly performed, can compromise limb salvage surgery and patient survival. The aim of the present paper is to examine the early management of such patients referred to the Department of Orthopaedic Surgery, Royal Prince Alfred Hospital, Sydney, Australia with particular reference to biopsy. We conducted a prospective audit of all patients referred to our musculoskeletal tumour service during 2002. Inclusion criteria were: all patients with primary tumours of the musculoskeletal system. We compared the outcome of patients biopsied prior to referral with that of patients biopsied in a recognized treatment centre. One hundred and forty-two patients were included. The referring surgeon performed biopsies in 29 cases, of which 20 were malignant lesions. The senior author biopsied the remaining 113 cases, of which 57 were malignant. Definitive treatment was hindered by a badly performed biopsy in 38% of patients biopsied by the referring surgeon. In 25% the definitive treatment had to be changed either to a more radical procedure than would have originally been necessary or to palliative rather than curative intent. Patients biopsied elsewhere were more likely to have an incom...Continue Reading

References

May 1, 1991·The Journal of Bone and Joint Surgery. British Volume·D J StokerJ A Pringle
Jan 1, 1989·Journal of Clinical Epidemiology·L J EmrichC P Karakousis
Feb 1, 1995·The British Journal of Surgery·C ZornigS Schröder
Apr 1, 1993·The Journal of Bone and Joint Surgery. American Volume·M A Simon, H A Finn
May 1, 1996·The Journal of Bone and Joint Surgery. American Volume·S NoriaR Bell
May 1, 1996·The Journal of Bone and Joint Surgery. American Volume·H J MankinM A Simon
Jul 1, 1997·Annals of Surgical Oncology·M J HeslinM F Brennan
May 16, 2000·Clinical Orthopaedics and Related Research·W G Ward, S Kilpatrick
Jan 5, 2002·The Journal of Bone and Joint Surgery. British Volume·C H GerrandA M Davis

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Citations

Dec 4, 2012·Indian Journal of Surgical Oncology·Ajay Puri, Ashish Gulia
May 4, 2011·American Journal of Clinical Oncology·B Ashleigh GuadagnoloYa-Chen Tina Shih
Jul 21, 2011·Indian Journal of Orthopaedics·Ajay Puri, Ashish Gulia
Jun 17, 2014·Indian Journal of Orthopaedics·Zile Singh Kundu
Jan 17, 2015·Indian Journal of Orthopaedics·Ajay Puri
Sep 6, 2014·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Ajay Puri
Nov 15, 2012·World Journal of Surgical Oncology·Jagajeevan JagadeesanRobert U Ashford
Jul 3, 2004·ANZ Journal of Surgery·Ian C DickinsonPeter F M Choong
Sep 1, 2006·The Journal of Bone and Joint Surgery. British Volume·R U AshfordP D Stalley
Oct 21, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·George S TamvakopoulosRobin Pollock

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