Biopterin in human brain and urine from controls and parkinsonian patients: application of a new radioimmunoassay

Clinica Chimica Acta; International Journal of Clinical Chemistry
T NagatsuH Narabayashi

Abstract

Total biopterin concentrations in the post-mortem human brain (caudate nucleus) and in the urine of controls and parkinsonian patients were measured by a newly developed radioimmunoassay. There was good correlation between the total biopterin level and tyrosine hydroxylase activity in the human brain. Biopterin concentrations in the caudate nucleus were greatly reduced in parkinsonian patients. In contrast, the reduction of urinary biopterin in parkinsonian patients was slight and not statistically significant, as compared with normal controls.

References

Mar 1, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·T NagatsuM Sano
May 1, 1979·Journal of Neurochemistry·R A LevineW Lovenberg
Oct 1, 1979·Experimental Neurology·S GauthierT L Sourkes
Jun 21, 1978·Pflügers Archiv : European journal of physiology·D A HäberleH Rembold
Nov 1, 1974·The American Journal of Clinical Nutrition·H BakerS H Hunter
Jul 1, 1973·Sabouraudia·K IwataT Hiratani
Nov 1, 1967·Analytical Biochemistry·G GuroffA Abramowitz
Jan 1, 1981·Analytical Biochemistry·T NagatsuH Ogawa
Feb 1, 1980·Analytical Biochemistry·T Fukushima, J C Nixon

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Citations

Jan 1, 1986·Journal of Neural Transmission·W Birkmayer, J G Birkmayer
Jan 1, 1985·Journal of Neural Transmission·M SawadaH Narabayashi
Jan 1, 1995·Journal of Neural Transmission. General Section·T NomuraT Nagatsu
Jan 1, 1995·Journal of Neural Transmission. General Section·I NagatsuT Nagatsu
Jan 1, 1993·Journal of Neural Transmission. Parkinson's Disease and Dementia Section·K VreckoJ Krainz
Jan 1, 1996·Journal of Biomedical Science·M.J. TsaiE.H.Y. Lee
Jan 1, 1989·Journal of Neural Transmission. Parkinson's Disease and Dementia Section·W BirkmayerE Ott
Oct 22, 2010·Journal of Neurology·Alexander L Berry, Thomas Foltynie
Apr 27, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·M SawadaT Nagatsu
Apr 1, 1992·Journal of the Neurological Sciences·Y FurukawaH Narabayashi
Aug 1, 1992·Journal of the Neurological Sciences·Y FurukawaY Mizuno
Oct 1, 1991·Neuroscience Research·T Nagatsu
Jan 1, 1983·Neurochemistry International·T Nagatsu
Aug 1, 1995·Neurochemistry International·M J Tsai, E H Lee
Jun 3, 1999·Biochimica Et Biophysica Acta·K FujimotoS Katoh
Mar 23, 2000·Progress in Neurobiology·K KoshimuraY Kato
Feb 1, 1986·Archives of Disease in Childhood·I SmithK Hyland
Oct 16, 1999·Proceedings of the National Academy of Sciences of the United States of America·O CortiJ Mallet
Feb 1, 1984·Psychiatry Research·D S DuchJ C Garbutt
May 1, 1991·The International Journal of Neuroscience·R Sandyk, S R Kay
Aug 12, 2009·Pediatric Neurology·Deniz YilmazYavuz Gürer
Feb 3, 2007·Brain Research·Jennifer E TobinRichard H Myers
Aug 1, 1989·Medical Hypotheses·M Rabinoff
Jun 1, 1989·Acta Neurologica Scandinavica·I C DissingV Rasmussen
Oct 1, 1995·Biological Psychiatry·M T Abou-SalehJ A Blair
Nov 16, 2014·Brain : a Journal of Neurology·Brent J RyanRichard Wade-Martins
Jul 10, 2010·Neuroscience and Biobehavioral Reviews·Karen L Eskow JaunarajsChristopher Bishop
Jan 1, 1989·Acta Neurologica Scandinavica. Supplementum·W Birkmayer, G J Birkmayer
Sep 1, 1987·Journal of Autonomic Pharmacology·T HataE Itoh

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