Biosynthesis of riccionidins and marchantins is regulated by R2R3-MYB transcription factors in Marchantia polymorpha

Journal of Plant Research
Hiroyoshi KuboKimitsune Ishizaki

Abstract

R2R3-MYB transcription factors constitute the largest gene family among plant transcription factor families. They became largely divergent during the evolution of land plants and regulate various biological processes. The functions of R2R3-MYBs are mostly characterized in seed plants but are poorly understood in non-seed plants. Here, we examined the function of two R2R3-MYB genes of Marchantia polymorpha (Mapoly0073s0038 and Mapoly0006s0226) that are closely related to subgroup 4 of the R2R3-MYB family. We performed LC/MS/MS metabolomics, RNA-seq analysis and expression analysis in overexpressors and knockout mutants of MpMYB14 and MpMYB02. Overexpression of MpMYB14 remarkably increased the amount of riccionidins, which are specific anthocyanins in liverworts and a few flowering plants. In contrast, overexpression of MpMYB02 increased the amount of several marchantins, which are characteristic cyclic bis (bibenzyl ether) compounds in M. polymorpha and related liverworts. Knockouts of MpMYB14 and MpMYB02 abolished the accumulation of riccionidins and marchantins, respectively. The expression of MpMYB14 was up-regulated by UV-B irradiation, N deficiency, and NaCl treatment, whereas the expression of MpMYB02 was down-regulated by...Continue Reading

References

Dec 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M SchenaR W Davis
Oct 1, 1996·Archives of Biochemistry and Biophysics·G HsiaoF N Ko
Mar 1, 1997·The Plant Journal : for Cell and Molecular Biology·T Aoyama, N H Chua
Mar 7, 1998·Journal of Molecular Evolution·J A Rosinski, W R Atchley
Aug 6, 1998·Bioscience, Biotechnology, and Biochemistry·T YamaguchiJ Terao
Dec 5, 1998·The Plant Journal : for Cell and Molecular Biology·H D KranzB Weisshaar
Feb 15, 2001·Trends in Plant Science·J K Zhu
Jun 21, 2001·Journal of Agricultural and Food Chemistry·S Burda, W Oleszek
Oct 13, 2001·Current Opinion in Plant Biology·R StrackeB Weisshaar
Dec 24, 2003·The Plant Journal : for Cell and Molecular Biology·Lisa J NewmanMalcolm M Campbell
Dec 31, 2003·Phytochemistry·Jim M DunwellSawsan Khuri
Feb 8, 2005·Current Biology : CB·Nicolas RotmanDavid Twell
Jan 7, 2006·Journal of Experimental Botany·Ivan CouéeAbdelhak El Amrani
Jul 5, 2007·Rapid Communications in Mass Spectrometry : RCM·Jie XingHongxiang Lou
Sep 12, 2007·Bioinformatics·M A LarkinD G Higgins
Nov 27, 2007·The Plant Journal : for Cell and Molecular Biology·Antonio GonzalezAlan M Lloyd
Jun 6, 2008·The Plant Journal : for Cell and Molecular Biology·Christian DubosLoïc Lepiniec
Feb 13, 2009·Plant Physiology·Felix LippoldMichael K Udvardi
Mar 21, 2009·PLoS Genetics·Lynette BrownfieldDavid Twell
Aug 3, 2010·Trends in Plant Science·Christian DubosLoïc Lepiniec
Nov 30, 2011·Plant & Cell Physiology·Farit Mochamad AfendiShigehiko Kanaya

❮ Previous
Next ❯

Citations

Sep 19, 2019·Proceedings of the National Academy of Sciences of the United States of America·Helge BerlandØyvind M Andersen
Aug 21, 2019·Frontiers in Plant Science·Keiko Yonekura-SakakibaraRyo Nakabayashi
Mar 3, 2020·Frontiers in Plant Science·Kevin M DaviesKathy E Schwinn
Dec 3, 2020·Nature Communications·Takehiko KanazawaTakashi Ueda
Dec 29, 2020·The New Phytologist·Facundo Romani, Javier E Moreno
Nov 12, 2020·International Journal of Molecular Sciences·Félix Rico-ReséndizAlfredo Cruz-Ramírez

❮ Previous
Next ❯

Datasets Mentioned

BETA
DRA005914
PRJ
DB5890

Methods Mentioned

BETA
environmental stress
PCR
reverse transcription-PCR
RNA-seq
transgenic
environmental stresses

Software Mentioned

Cuffdiff
ClustalW
NJplot

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.