Biosynthesis of the halogenated auxin, 4-chloroindole-3-acetic acid.

Plant Physiology
Nathan D TivendaleJohn J Ross

Abstract

Seeds of several agriculturally important legumes are rich sources of the only halogenated plant hormone, 4-chloroindole-3-acetic acid. However, the biosynthesis of this auxin is poorly understood. Here, we show that in pea (Pisum sativum) seeds, 4-chloroindole-3-acetic acid is synthesized via the novel intermediate 4-chloroindole-3-pyruvic acid, which is produced from 4-chlorotryptophan by two aminotransferases, TRYPTOPHAN AMINOTRANSFERASE RELATED1 and TRYPTOPHAN AMINOTRANSFERASE RELATED2. We characterize a tar2 mutant, obtained by Targeting Induced Local Lesions in Genomes, the seeds of which contain dramatically reduced 4-chloroindole-3-acetic acid levels as they mature. We also show that the widespread auxin, indole-3-acetic acid, is synthesized by a parallel pathway in pea.

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Citations

Feb 14, 2014·Trends in Plant Science·Nathan D TivendaleJerry D Cohen
Apr 13, 2013·Journal of Experimental Botany·David A KorasickLucia C Strader
Apr 9, 2014·Proceedings of the National Academy of Sciences of the United States of America·Michael G MasonChristine A Beveridge
Aug 19, 2014·Trends in Plant Science·Jipei YueJinling Huang
Dec 18, 2013·Physiologia Plantarum·Richard J PattisonCarmen Catalá
Jun 24, 2014·The Arabidopsis Book·Yunde Zhao
Sep 15, 2015·Bioscience, Biotechnology, and Biochemistry·Hiroyuki Kasahara
Oct 18, 2012·Plant Signaling & Behavior·John J RossJason A Smith
Nov 4, 2016·Plant Signaling & Behavior·Sam D Cook, John J Ross
Jul 28, 2017·The New Phytologist·Erin L McAdamJohn J Ross
Dec 2, 2017·International Journal of Molecular Sciences·Damilola OlatunjiInge Verstraeten
Jan 10, 2018·Frontiers in Plant Science·Siva K Malka, Youfa Cheng
Feb 11, 2015·American Journal of Botany·Tara A Enders, Lucia C Strader
Jan 17, 2019·Plant & Cell Physiology·Sam D Cook
Mar 4, 2020·International Journal of Molecular Sciences·Jinshan CaoYouning Wang
Mar 17, 2020·Annual Review of Plant Biology·Joseph R Jacobowitz, Jing-Ke Weng
Apr 11, 2020·International Journal of Molecular Sciences·Antje WalterJutta Ludwig-Müller
Sep 29, 2020·The New Phytologist·Tobias MeitzelLjudmilla Borisjuk
Dec 18, 2020·Frontiers in Plant Science·Katharine DavisSarah E O'Connor
Aug 15, 2013·Plant Physiology·Alexandre de Saint GermainCatherine Rameau
Feb 14, 2013·Development·Karin Ljung

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