PMID: 9446330Jan 31, 1998Paper

Biotechnological approaches to the development of therapeutic and diagnostic preparations of lipid nature

Voprosy medit︠s︡inskoĭ khimii
V I ShvetzA E Stepanov

Abstract

The paper summarizes own results of studies on phospholipids and glycolipids from natural biological sources. New approaches for synthesis of inositol-containing sphingophospholipids, glycophosphatidylinositols, semisynthetic synthesis of phosphoglycerols have been introduced. New industrial method of phosphjatidylcholine isolation and production of number of lipid preparations were developed. Incorporation of DOPA into liposomes increases efficacy of its action in the medication of MPTP-induced parkinsonism in mice.

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