Feb 1, 1992

Biphasic constriction of rabbit basilar artery following experimental subarachnoid hemorrhage: a morphometric study

Surgical Neurology
H JohshitaH Ogawa


To assess the changes in arterial structure resulting from subarachnoid hemorrhage, morphometric analysis was performed on basilar arteries from rabbits that had received an experimental subarachnoid hemorrhage up to 6 days earlier. For morphometric determination, the cross-sectional area of the media, the area of the lumen, and the length of the internal elastic lamina were measured planimetrically. The morphometric diameter of the lumen, the media-to-radius ratio, and several other morphometric parameters were also calculated. Subarachnoid hemorrhage induced significant biphasic constriction of the basilar artery without any changes in the cross-sectional area of the media. The relative amount of smooth muscle cell decreased significantly in the late stage of hemorrhage.

Mentioned in this Paper

Subarachnoid Hemorrhage, Spontaneous
Chinchilla Rabbits
Subarachnoid Hemorrhage
Oculocerebral Hypopigmentation Syndrome Type Preus
Structure of Basilar Artery

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