Abstract
Biphasic insulin aspart 30 (BIAsp 30 [30% soluble, rapid-acting insulin aspart and 70% protamine-bound insulin aspart], NovoLog Mix 70/30, Novo Nordisk, Bagsvaerd, Denmark), a premixed insulin analogue, addresses both the prandial and basal aspects of glucose regulation when used once or twice daily in patients with type 1 or type 2 diabetes. It provides overall glycemic control similar to biphasic human insulin 30 (BHI 30, 30% human insulin and 70% neutral protamine Hagedorn [NPH] insulin) in patients with type 1 or type 2 diabetes. The aim of this review was to evaluate the safety profile associated with BIAsp 30 in patients with type 1 or type 2 diabetes versus that of comparator insulin products, including BHI 30 and biphasic insulin lispro 25 (Mix 25 [25% biphasic insulin lispro and 75% protaminated lispro], Humalog Mix 75/25, Eli Lilly and Company, Indianapolis, Indiana), together with the basal insulins, including NPH insulin and insulin glargine (Lantus, Sanofi-Aventis Pharmaceuticals, Paris, France). Data from human clinical studies published in peer-reviewed journals or as conference proceedings that reported safety results in patients with type 1 or type 2 diabetes who were treated with BIAsp 30 versus comparator ins...Continue Reading
References
Nov 12, 1992·The New England Journal of Medicine·H Yki-JärvinenP Seppälä
Nov 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·A VølundJ Schlichtkrull
May 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·L Heinemann
Sep 30, 1993·The New England Journal of Medicine·UNKNOWN Diabetes Control and Complications Trial Research GroupC Siebert
Apr 1, 1996·The Biochemical Journal·B F HansenA G Lundemose
Dec 1, 1996·Diabetologia·M HanefeldJ Lindner
Oct 7, 1997·Diabetes Care·C WeyerL Heinemann
Nov 5, 1998·Diabetes Care·P D HomeP Round
May 20, 1999·Diabetes Care·A LindholmA P Riis
Jun 18, 1999·Diabetes Care·M TominagaA Sekikawa
Oct 8, 1999·Diabetic Medicine : a Journal of the British Diabetic Association
Jun 15, 2000·European Journal of Clinical Pharmacology·H E Turner, D R Matthews
Jun 24, 2000·Diabetes·P KurtzhalsT Trüb
Sep 29, 2000·European Journal of Clinical Pharmacology·L V JacobsenA Riis
Feb 7, 2002·Expert Opinion on Pharmacotherapy·Simon HellerAnders Lindholm
Apr 30, 2002·Diabetes Care·Anders LindholmJacob Råstam
Apr 30, 2002·Diabetes Care·Kjeld HermansenSten Madsbad
May 25, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·B O BoehmA Lindholm
Jan 30, 2004·Clinical Therapeutics·Itamar RazIlana Harman-Boehm
Jun 16, 2004·Circulation·Katherine EspositoUNKNOWN Campanian Postprandial Hyperglycemia Study Group
Aug 17, 2004·The Medical Clinics of North America·Trent Davis, Steven V Edelman
Sep 15, 2004·Diabetes Research and Clinical Practice·Mark L WarrenElsie Allen
Jan 26, 2005·European Journal of Internal Medicine·Bernhard O BoehmPhilip D Home
Jan 29, 2005·Diabetes Care·Philip RaskinUNKNOWN INITIATE Study Group
Citations
Sep 22, 2009·Advances in Therapy·Robert E Rakel
Jun 21, 2013·Gene Therapy·S VasuP R Flatt
Feb 14, 2008·Diabetes, Obesity & Metabolism·D KhutsoaneUNKNOWN PRESENT Study Group
May 23, 2008·Diabetes, Obesity & Metabolism·Y GaoUNKNOWN PRESENT Study Group
May 16, 2008·International Journal of Clinical Practice·H C JangUNKNOWN PRESENT Study Group
Dec 21, 2010·International Journal of Clinical Practice·S LevitJ Wainstein
Jul 2, 2009·PloS One·Christine ClarNorman Waugh
Jun 20, 2014·PloS One·Yafang HuangJinling Tang
Jun 23, 2009·Expert Opinion on Drug Safety·Joanna Mitri, Osama Hamdy
Nov 16, 2007·Expert Opinion on Pharmacotherapy·N M LalićM Vujasin
May 10, 2013·Diabetes Research and Clinical Practice·Zafar Ahmed LatifS M Ashrafuzzaman
Apr 1, 2008·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Santiago Durán GarcíaAlfonso Pumar López
Nov 17, 2007·Current Medical Research and Opinion·M ShestakovaS Guler
Jan 25, 2008·Current Medical Research and Opinion·S K SharmaJ A Vaz
Jan 31, 2008·Diabetes/metabolism Research and Reviews·Patrick J Boyle, John Zrebiec
Oct 19, 2016·PharmacoEconomics·Asrul Akmal ShafieNathorn Chaiyakunapruk
Oct 16, 2015·BMC Endocrine Disorders·Marcin CzechMichał Jakubczyk
Jun 10, 2016·BMC Endocrine Disorders·Amir FarshchiAlireza Esteghamati
Nov 26, 2009·Expert Opinion on Pharmacotherapy·Domenico Cucinotta, Giuseppina T Russo