PMID: 9556746Apr 29, 1998Paper

Biphasic spiral computed tomography for detection of hepatocellular carcinoma before resection or orthotopic liver transplantation

Investigative Radiology
E Lopez HänninenR Felix

Abstract

The authors correlate computed tomography (CT) findings in biphasic spiral technique with histopathology in patients with hepatocellular carcinoma (HCC) who had undergone liver resection (LR) or orthotopic liver transplantation (OLT). Preoperative biphasic spiral CT findings in 33 consecutive patients (23 men, 10 women, aged 43-74 years; LR group: n = 17; OLT group; n = 16) with liver cirrhosis and HCC were reviewed retrospectively by consensus of two radiologists and correlated with pathology from liver specimens. Of the 16 patients in the OLT group with 1 to 5 confirmed HCC lesions (total lesions: 29; mean lesion diameter: 2 cm; range: 0.6-5.0 cm), CT before OLT depicted 22 lesions in 15 patients (sensitivity for lesions with a diameter of 0.5-1.0 cm, 20%; for lesions 1.1-2.0 cm, 82%; and for lesions 2.1-3.0 cm and > 3.0 cm, 86% and 100%, respectively). Among the 17 patients in the LR group (total lesions: 21; mean lesion diameter: 5.4 cm; range: 1.0-11.0 cm), CT detected 18 lesions. Lesion-by-lesion sensitivity, as correlated with pathology, was calculated at 76% and 86% in the OLT and LR groups, respectively (overall sensitivity, 80%). The diameter of CT detected lesions, compared with liver specimens, corresponded in 90% o...Continue Reading

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Citations

Jan 18, 2003·Current Gastroenterology Reports·Miguel R Arguedas
Jan 30, 2004·Clinical Radiology·S C H YuN M C So
Jun 14, 2000·Journal of Hepatology·M A KhanA M Di Bisceglie
Apr 22, 2003·AJR. American Journal of Roentgenology·Isaac R FrancisKartik I Ragupathi
Mar 19, 2009·World Journal of Gastroenterology : WJG·Asmaa I GomaaSimon D Taylor-Robinson
Nov 30, 2004·Liver International : Official Journal of the International Association for the Study of the Liver·Takuma TerataniOmata Masao
Nov 13, 2008·Transplant International : Official Journal of the European Society for Organ Transplantation·Timm DeneckeEnrique Lopez Hänninen
Apr 6, 2002·Clinics in Liver Disease·Hero K Hussain, Hanh Vu Nghiem
Dec 11, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Glenn A KrinskyA S Goldenberg
Aug 14, 2009·Expert Review of Gastroenterology & Hepatology·Mohamed I F ShariffSimon D Taylor-Robinson
Dec 10, 1999·Investigative Radiology·V M Runge
May 1, 2002·European Journal of Gastroenterology & Hepatology·Victor de LédinghenJacques Drouillard

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