Bipolar disorder and its outcomes: two cohorts, 1875-1924 and 1994-2007, compared

History of Psychiatry
Onome V AtigariDavid Healy

Abstract

We compared admission rates and outcomes for bipolar disorder patients using the medical records of patients with a first hospital admission in 1875-1924 retrospectively diagnosed based on International Classification of Diseases (ICD)-10 criteria, and patients with a first admission in 1994-2007. The incidences of first admissions in the historical and contemporary periods are comparable: 1.2 and 1.3 per hundred thousand per year, respectively. Manic episodes constituted a greater proportion of admissions historically, while depressive episodes made up more in the contemporary sample. There is no evidence for a reduction in the mean inter-admission intervals with duration of illness. This study suggests that modern treatments may have decreased lengths of stay in hospital, but at a cost of contributing to more admissions. It also points to a shift in the threshold for admissions.

References

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Jul 19, 2001·Psychological Medicine·D HealyE Susser
Nov 2, 2004·The British Journal of Psychiatry : the Journal of Mental Science·Lars Vedel KessingPer Kragh Andersen
Feb 3, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Tuhina LloydUNKNOWN AESOP study team
Jun 29, 2005·History of Psychiatry·David HealyDavid Hirst
Feb 3, 2006·History of Psychiatry·Margaret HarrisDavid Healy
Jul 8, 2011·Journal of Affective Disorders·Margaret HarrisAnthony P Roberts

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Citations

Feb 26, 2011·Globalization and Health·Celia IriartEmerson E Merhy
Oct 10, 2021·Brain and Behavior·María Yoldi-NegreteBeatriz Camarena Medellín

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