Bipolar symptoms in adult attention-deficit/hyperactivity disorder: a cross-sectional study of 510 clinically diagnosed patients and 417 population-based controls

The Journal of Clinical Psychiatry
A HalmøyJ Haavik

Abstract

Bipolar spectrum disorders (BSD) have several symptoms and features in common with attention-deficit/hyperactivity disorder (ADHD). Here we explored the prevalence of BSD and the relationship between symptoms of BSD and ADHD in adult ADHD patients. Norwegian adults diagnosed with DSM-IV ADHD during 1997 through 2007 (n = 510) and a random sample of 417 controls from the general population (aged 18-40 years) were recruited and responded to 85 questions rating symptoms of ADHD, lifetime symptoms of mood disorders, other comorbid conditions, and sociodemographic data. According to the Mood Disorder Questionnaire (MDQ), 50.6% of the ADHD patients screened positive for BSD, compared to 8.3% of the controls. In comparison, the prevalence of BSD according to DSM-IV in a subsample of interviewed patients (n = 50) was 32%. In the whole study sample (N = 927), an ADHD diagnosis was the strongest predictor for screening positive on the MDQ (OR = 5.0, P < .001), but the correlation between dimensional symptom levels of ADHD and of BSD was strongest in the control group (Pearson correlation r = 0.7, P < .001 vs r = 0.3, P < .001). Patients screening positive on the MDQ had significantly more drug problems, higher ADHD symptom scores, and lo...Continue Reading

Citations

Mar 12, 2011·European Archives of Psychiatry and Clinical Neuroscience·Ole Bernt FasmerJan Haavik
Jul 4, 2012·International Archives of Occupational and Environmental Health·Thomas KüpperBarbara Schauble
May 29, 2012·Journal of Affective Disorders·Caroline SkirrowPhilip Asherson
May 23, 2012·Journal of the International Neuropsychological Society : JINS·Helene Barone HallelandAstri J Lundervold
Jul 14, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Andreas ReifKlaus-Peter Lesch
Jun 10, 2010·Genes, Brain, and Behavior·K J OedegaardJ R Kelsoe
Feb 1, 2011·Genes, Brain, and Behavior·E T LandaasJ Haavik
Aug 9, 2011·BMC Psychiatry·Ole Bernt FasmerJan Haavik
Sep 15, 2015·Expert Opinion on Pharmacotherapy·Giulio Perugi, Giulia Vannucchi
Feb 8, 2013·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Kaya K JacobsenStefan Johansson
Jul 29, 2011·Behavioral and Brain Functions : BBF·Astri J LundervoldJan Haavik
Feb 25, 2014·Psychiatry Research·Thegna MavroconstantiJan Haavik
Nov 2, 2013·Research in Developmental Disabilities·Maj-Britt PosserudAstri J Lundervold
Sep 25, 2016·Journal of Attention Disorders·Johanne Telnes InstanesJan Haavik
Feb 2, 2017·Current Psychiatry Reports·Giulio PerugiEttore Favaretto
Nov 26, 2013·Journal of Attention Disorders·Johanne Telnes InstanesAnne Halmøy
Jan 4, 2015·Journal of Attention Disorders·Helene B HallelandAstri J Lundervold
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Nov 7, 2015·Behavioral and Brain Functions : BBF·Tore Ivar Malmei AarslandJan Haavik
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Jan 2, 2021·Frontiers in Psychology·Astri J LundervoldJocelyn I Meza
Jan 31, 2021·Neuroscience and Biobehavioral Reviews·Carmen SchiweckAndreas Reif

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