Birth and death of duplicated genes in completely sequenced eukaryotes

Trends in Genetics : TIG
A Wagner

Abstract

Gene and genome duplications are commonly regarded as being of major evolutionary significance. But how often does gene duplication occur? And, once duplicated, what are the fates of duplicated genes? How do they contribute to evolution? In a recent article, Lynch and Conery analyze divergence between duplicate genes from six eukaryotic genomes. They estimate the rate of gene duplication, the rate of gene loss after duplication and the strength of selection experienced by duplicate genes. They conclude that although the rate of gene duplications is high, so is the rate of gene loss, and they argue that gene duplications could be a major factor in speciation.

References

Jun 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M Kimura, J L King
Apr 12, 1979·Journal of Molecular Evolution·S D Ferris, G S Whitt
Jan 20, 1977·Nature·S D Ferris, G S Whitt
May 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·T Ohta
Jan 1, 1987·Genetics·T Ohta
Apr 12, 1994·Proceedings of the National Academy of Sciences of the United States of America·A G Clark
Jul 10, 1997·Nature·M A NowakJ M Smith
May 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·C Seoighe, K H Wolfe
Nov 10, 2000·Science·M Lynch, J S Conery
Dec 29, 2000·Nature·UNKNOWN Arabidopsis Genome Initiative
Nov 1, 1983·Genetics·G A Watterson

❮ Previous
Next ❯

Citations

Dec 8, 2009·Biochemical Genetics·Jing WangTing Wang
Sep 2, 2008·Plant Molecular Biology·Angela Raffaella CiarbelliIda Ruberti
Jan 16, 2004·Insect Biochemistry and Molecular Biology·Ben J Mans, Albert W H Neitz
Jan 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·Ran KafriYitzhak Pilpel
Apr 11, 2003·Diabetes Technology & Therapeutics·David W Moskowitz
Dec 9, 2004·Bioinformatics·Julian Gough
May 30, 2006·The Plant Cell·Alexandra ToFrançois Parcy
Apr 20, 2005·BMC Plant Biology·Tatsuya FukudaMasayuki Maki
Jan 5, 2007·Genome Biology·Albert ZlotnikHisayuki Nomiyama
Aug 4, 2009·PLoS Computational Biology·Xingyi GuoDeyou Zheng
Mar 23, 2005·Genetics·Allan ForceMichael Lynch
Dec 3, 2005·Genetics·Paul F CliftenMark Johnston
Jul 11, 2012·International Journal of Evolutionary Biology·Guillaume DissChristian R Landry
Oct 13, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·T MassinghamP Liò
Sep 2, 2004·Protein Science : a Publication of the Protein Society·Michael J Behe, David W Snoke
Feb 18, 2004·EMBO Reports·Gregory D AmoutziasErich Bornberg-Bauer
Apr 4, 2016·Journal of Theoretical Biology·Loren HaarsmaPeter VandeHaar
Mar 13, 2003·Experimental Dermatology·A Kljuic, A M Christiano
Feb 13, 2007·Gene·Jorge M O FernandesIan A Johnston
Nov 24, 2004·Journal of Molecular Evolution·Emilie GuldnerNicolas Galtier
Dec 16, 2006·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Jing LuoAxel Meyer
Nov 11, 2005·Molecular Biology and Evolution·Michael Lynch
Jul 1, 2007·Animal : an International Journal of Animal Bioscience·C JondrevilleY Nys
Apr 8, 2004·Molecular Genetics and Genomics : MGG·N SoranzoC Frova
Sep 16, 2005·Molecular Biology and Evolution·Karen D CrowGünter P Wagner
Sep 9, 2020·Scientific Reports·Lyubov E SalnikovaSerikbay K Abilev

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.