Birth weight and cardiovascular risk factors in an epidemiological study

Diabetologia
E VestboC E Mogensen

Abstract

Low birth weight has been proposed as a risk factor for development of non-insulin-dependent diabetes mellitus, hypertension, and cardiovascular disease in the adult. To ascertain the extent to which birth weight was associated with cardiovascular risk factors, we examined 620 subjects (median age 48 years) in a cross-sectional study. Of these 317 were offspring of diabetic patients and 303 were offspring of non-diabetic control subjects. Known risk factors for development of cardiovascular disease were correlated to birth weight and examined as dependent variables by multiple linear regression. Age, body mass index (BMI), subjects gender along with parental gender, diabetes status of the parents, and birth weight were independent variables. The variance of the risk factors as dependent variables explained by age, gender, and BMI as independent variables was examined and birth weight was added as an independent variable. We found birth weight was inconsistently correlated to the different risk factors in the different groups of subjects. When adjusted for age, BMI, subject's gender, parental gender, and the diabetes status of the parents, birth weight was negatively correlated to fasting blood glucose. In offspring of diabetic ...Continue Reading

Citations

Mar 20, 2003·Current Diabetes Reports·Delphine JaquetClaire Levy-Marchal
Mar 20, 2003·Current Diabetes Reports·Kevin RowleyJames D Best
Oct 1, 2010·Journal of Developmental Origins of Health and Disease·K PilgaardT Jørgensen
Jul 17, 1997·The New England Journal of Medicine·F Holleman, J B Hoekstra
Dec 16, 1998·British Journal of Obstetrics and Gynaecology·P Steer
Aug 23, 2001·Journal of Pediatric Endocrinology & Metabolism : JPEM·F L FrazerG C Byrne
Mar 7, 2009·International Journal of Biological Sciences·Maria BanciFulvia Gloria-Bottini
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sarah L WhiteRachel R Huxley
May 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·C A NewsomeC M Law
Feb 10, 2010·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Muhammad Bayu SasongkoJie Jin Wang
Sep 15, 2006·Archives of Medical Research·Marcelino Hernandez-Valencia, Mary-Elizabeth Patti
Jul 26, 2005·Annals of Epidemiology·Debbie A LawlorGeorge Davey Smith
Feb 13, 2003·Obesity Research·Saskia J Te VeldeHan C G Kemper
Oct 16, 2003·International Journal of Epidemiology·Liisa LaurénUNKNOWN EURO-BLCS Study Group
Jan 26, 2002·British Medical Bulletin·C N Hales, D J Barker
Jan 13, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Paula M L SkidmoreMichael E J Wadsworth
Jun 25, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·I Rogers, UNKNOWN EURO-BLCS Study Group
May 9, 2000·The American Journal of Clinical Nutrition·P J Steer
May 16, 2017·The Journal of Obstetrics and Gynaecology Research·Shinji KatsuragiYoshihiro Miyamoto

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.