Bisoprolol transdermal patch treatment for patients with atrial fibrillation after noncardiac surgery: A single-center retrospective study of 61 patients

SAGE Open Medicine
Taku YasuiMasashi Fujita

Abstract

Atrial fibrillation after surgery is associated with increased rates of heart failure and ischemic stroke, and extension of hospitalization. Bisoprolol is a β-blocker used to reduce heart rate and manage arrhythmias during atrial fibrillation. However, the safety and efficacy of bisoprolol transdermal patch treatment in patients with postoperative atrial fibrillation remain unclear. We retrospectively assessed the electronic health records of our hospital between September 2013 and July 2018 and identified patients with postoperative atrial fibrillation who had been treated with a bisoprolol transdermal patch. We excluded patients with sinus rhythm using bisoprolol transdermal patch to prevent atrial fibrillation recurrence and those with sustained atrial fibrillation before surgery. Data on heart rhythm, heart rate, and blood pressure at the baseline and after 24 h of treatment were obtained from the electronic health records. Of the 603 patients treated with the bisoprolol transdermal patch, 61 patients with postoperative atrial fibrillation after noncardiac surgery were included. The bisoprolol transdermal patch was discontinued due to bradycardia in two patients (3.3%). In both cases, the heart rate increased after the remo...Continue Reading

References

Sep 19, 2003·Current Medical Research and Opinion·Daniel E HillemanKathleen A Packard
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Ara A VaporciyanJoe B Putnam
Aug 15, 2014·JAMA : the Journal of the American Medical Association·Gino GialdiniHooman Kamel
Jul 8, 2015·Journal of Thrombosis and Haemostasis : JTH·A BessissowP Alonso-Coello
Apr 5, 2016·The New England Journal of Medicine·A Marc GillinovUNKNOWN CTSN

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