Bispectral index, spectral edge frequency 95% and median frequency recorded at varying desflurane concentrations in pigs

Research in Veterinary Science
María F Martín-CanchoJesús Usón-Gargallo

Abstract

The objective of this study is to evaluate the usefulness of bispectral index (BIS), spectral edge frequency 95% (SEF) and median frequency (MED) in relation to a simple descriptive scale (SDS) as indicators of anaesthetic depth at different desflurane concentrations in swine. Sixteen pigs were randomly allocated to four groups. Electroencephalograms (EEG) were recorded during desflurane anaesthesia, and BIS, SEF and MED were calculated from the EEG. The agent was administered in pure oxygen at 1, 1.25, 1.5 and 1.7 MAC in randomized order. Anaesthetic depth was evaluated on a SDS. BIS decreased significantly (P<0.001) at the different anaesthetic dosages used. SEF decreased significantly (P<0.001) from basal to 1 MAC of desflurane. MED decreased significantly (P<0.001) from basal to 1 MAC and from 1 to 1.75 MAC. Good correlation was seen between SDS scores and BIS values and between SDS scores and MED values. BIS appeared to be useful to predict changes in anaesthetic depth at clinically used dosages of inhalant anaesthesia.

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Citations

Jun 1, 2014·Physiology & Behavior·Dale A SandercockDorothy E F McKeegan
Mar 5, 2016·British Journal of Anaesthesia·A G Bradbury, R E Clutton
Aug 13, 2015·Research in Veterinary Science·M T W VerhoevenB Kemp
Mar 18, 2009·Journal of Veterinary Pharmacology and Therapeutics·S BrásC S Nunes
Oct 13, 2011·Veterinary Anaesthesia and Analgesia·Tamas D AmbriskoPaul Chambers
Apr 21, 2012·Laboratory Animals·Aura Silva, Luis Antunes
Nov 3, 2020·Journal of Veterinary Emergency and Critical Care·Phitchaya SaenubolSiwaporn Chankrachang
Sep 29, 2011·The Veterinary Record·P LlonchA Velarde

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