PMID: 22587287May 17, 2012Paper

Bistability and spatiotemporal irregularity in neuronal networks with nonlinear synaptic transmission

Physical Review Letters
Gianluigi MongilloCarl van Vreeswijk

Abstract

We present a mean-field theory for spiking networks operating in the balanced excitation-inhibition regime, with synapses displaying short-term plasticity. The theory reveals a novel mechanism for bistability which relies on the nonlinearity of the synaptic interactions. As synaptic nonlinearity is mainly controlled by the spiking rates, the different states are stabilized by dynamically generated changes in the noise level. Thus, in both states, the network operates in the fluctuation-driven regime, producing activity patterns characterized by strong spatiotemporal irregularity.

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Citations

Mar 6, 2015·Proceedings of the National Academy of Sciences of the United States of America·Gabriela MocholJaime de la Rocha
Apr 10, 2013·Neural Networks : the Official Journal of the International Neural Network Society·Vladimir P Zhdanov
Mar 25, 2014·Current Opinion in Neurobiology·Fred WolfAndreas Neef
Aug 23, 2017·ELife·Daniel JercogJaime de la Rocha
Apr 20, 2019·PLoS Computational Biology·Alexander SeeholzerWulfram Gerstner
May 17, 2013·Physical Review Letters·Kaare MikkelsenAlessandro Torcini
Jan 15, 2016·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·M UzuntarlaJ J Torres
Jul 15, 2017·Physical Review Letters·Davide Bernardi, Benjamin Lindner
Sep 18, 2020·PLoS Computational Biology·Alessandro SanzeniNicolas Brunel
Jul 1, 2020·ELife·Alessandro SanzeniMark H Histed
Mar 14, 2018·Proceedings of the National Academy of Sciences of the United States of America·Nataliya Kraynyukova, Tatjana Tchumatchenko
Feb 8, 2019·Cognitive Neurodynamics·Victor J BarrancaSida Li
Nov 5, 2019·Frontiers in Neuroscience·Victor J Barranca, Douglas Zhou
Apr 8, 2020·Journal of Mathematical Neuroscience·Valentin SchmutzTilo Schwalger
Sep 19, 2020·PLoS Computational Biology·Cody BakerRobert Rosenbaum
Jul 16, 2014·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Kaare MikkelsenAlessandro Torcini
May 11, 2021·Frontiers in Neural Circuits·Nikita NovikovBoris Gutkin
Sep 1, 2021·Neuron·Yashar Ahmadian, Kenneth D Miller

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