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Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease

Circulation. Genomic and Precision Medicine

Dec 1, 2018

Katherine M Siewert, Benjamin Franklin Voight

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Abstract

Plasma lipid levels are heritable and genetically associated with risk of coronary artery disease (CAD). However, genome-wide association studies (GWAS) routinely analyze these traits independent of one another. Joint GWAS for two related phenotypes can lead to a higher powered analysis...read more

Mentioned in this Paper

Cholesterol
Coronary Arteriosclerosis
Genes
Genome
Heart Diseases
Lipids
High Density Lipoprotein Cholesterol
Low-Density Lipoproteins
Plasma
Triglycerides
7
26
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Bivariate Genome-Wide Association Scan Identifies 6 Novel Loci Associated With Lipid Levels and Coronary Artery Disease

Circulation. Genomic and Precision Medicine

Dec 1, 2018

Katherine M Siewert, Benjamin Franklin Voight

PMID: 30525989

DOI: 10.1161/circgen.118.002239

Abstract

Plasma lipid levels are heritable and genetically associated with risk of coronary artery disease (CAD). However, genome-wide association studies (GWAS) routinely analyze these traits independent of one another. Joint GWAS for two related phenotypes can lead to a higher powered analysis...read more

Mentioned in this Paper

Cholesterol
Coronary Arteriosclerosis
Genes
Genome
Heart Diseases
7
26

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