Bizarre and scary ECG in yew leaves poisoning: Report of successful treatment

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Natascia CerratoEnzo Aluffi

Abstract

Yew leaves poisoning is a rare life-threatening intoxication, whose diagnosis can be difficult. Initial symptoms are nausea, vomiting, abdominal pain, dizziness, tachycardia, muscle weakness, confusion, beginning within 1 hr from ingestion and followed by bradycardia, ventricular arrhythmias, ventricular fibrillation, severe hypotension, and death. Taxine-derived alkaloids are responsible for the toxicity of the yew leaves, blocking sodium and calcium channels, and causing conduction abnormalities. Because of lack of a specific antidote and limited efficacy of common antiarrhythmic drugs, prompt diagnosis, detoxification measures, and immediate hemodynamic support (also with transvenous cardiac stimulation) are essential.

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Citations

May 30, 2021·The American Journal of Emergency Medicine·Mohammad Alarfaj, Ankur Goswami
Nov 16, 2021·Journal of Forensic Sciences·Elizabeth W L Brooks-LimAaron M Shapiro

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