Black and Hispanic women are less likely than white women to receive guideline-concordant endometrial cancer treatment.

American Journal of Obstetrics and Gynecology
Mara KaspersAshley S Felix

Abstract

Differences in receipt of guideline-concordant treatment might underlie well-established racial disparities in endometrial cancer mortality. Using the National Cancer Database, we assessed the hypothesis that among women with endometrioid endometrial cancer, racial/ethnic minority women would have lower odds of receiving guideline-concordant treatment than white women. In addition, we hypothesized that lack of guideline-concordant treatment was linked with worse survival. We defined receipt of guideline-concordant treatment using the National Comprehensive Cancer Network guidelines. Multivariable logistic regression models were used to compute odds ratios and 95% confidence intervals for associations between race and guideline-concordant treatment. We used multivariable Cox proportional hazards regression models to estimate hazards ratios and 95% confidence intervals for relationships between guideline-concordant treatment and overall survival in the overall study population and stratified by race/ethnicity. This analysis was restricted to the 89,319 women diagnosed with an invasive, endometrioid endometrial cancer between 2004 and 2014. Overall, 74.7% of the cohort received guideline-concordant treatment (n = 66,699). Analyses...Continue Reading

Citations

Jun 30, 2021·Current Opinion in Obstetrics & Gynecology·Kiran Clair, Robert E Bristow
Jul 15, 2021·Obstetrics and Gynecology·Victoria E RodriguezRobert E Bristow
Jul 14, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Andy M HabibJason A Brant
Aug 14, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Alli M StraubharKathryn A Maurer
Sep 7, 2021·Frontiers in Oncology·Diocésio Alves Pinto de AndradeRicardo Dos Reis

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