Black thyroid revisited: cytologic diagnosis in fine-needle aspirates is unlikely

Diagnostic Cytopathology
Yolanda C OertelEmmanuel A Fadeyi

Abstract

We report four patients diagnosed with black discoloration of the thyroid gland at surgery and a fifth patient in which the "black thyroid" was an incidental finding at autopsy. The four patients diagnosed at surgery had prior fine-needle aspirations (FNA), which did not reveal any characteristic pigmentation. One patient presented with cervical lymph node metastases from a papillary microcarcinoma of thyroid. The second patient was diagnosed as a cellular adenomatoid nodule, and suppressive therapy was recommended. She elected to have surgery instead. The third patient underwent surgery because of an oxyphilic cell nodule, in a background of lymphocytic thyroiditis, in which a Hürthle cell neoplasm could not be ruled out. His aspirates were reviewed at two other institutions, and no diagnosis of black thyroid was entertained. The fourth patient had an adenomatoid nodule with cystic change and slightly atypical squamous metaplasia. She decided to have surgery, which revealed a black thyroid. Later, it was discovered that the patients had received minocycline for the treatment of acne. FNA does not seem to be a reliable method to diagnose black thyroid preoperatively. Although this is a striking operative finding, diagnosing it ...Continue Reading

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Citations

Aug 15, 2013·Forensic Science, Medicine, and Pathology·Roger W Byard
Oct 25, 2007·Thyroid : Official Journal of the American Thyroid Association·Yolanda C Oertel
Jul 18, 2008·Thyroid : Official Journal of the American Thyroid Association·Lyndal TaconGreg Fulcher
Nov 30, 2010·International Journal of Endocrinology·Emad KandilByron Crawford
Aug 30, 2008·Endocrine Journal·Sang-Wook KangCheong Soo Park
Mar 19, 2011·Head & Neck·Emad KandilBernard M Jaffe
Nov 6, 2009·Diagnostic Cytopathology·Allison H S Hall, Sarah M Bean
Apr 10, 2016·The Journal of Pediatrics·Allison J PollockDavid B Allen
Jan 19, 2007·Diagnostic Cytopathology·Liron Pantanowitz
Nov 15, 2014·Ear, Nose, & Throat Journal·Darrin V BannDavid Goldenberg

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