Black tongue associated with linezolid

American Journal of Therapeutics
Francisco Jover-DiazCoral Martin-Gonzalez

Abstract

Darkening of the tongue and oral mucosa is a reaction pattern that can be related to a number of physiologic, metabolic, and toxic disorders, and medications and exogenous substances. Black discoloration of the tongue should be distinguished from black "hairy" tongue, which is characterized by hypertrophy of the filiform papillae. We report a case of a 42-year-old man presented with a black discoloration of his tongue during treatment with linezolid for spondylodiscitis. So in conclusion, tongue discoloration is a benign and reversible condition and a probable adverse event associated with linezolid. We present this case to increase clinicians' awareness of a new potential adverse effect of linezolid.

References

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Citations

Feb 19, 2013·Journal of Medical Case Reports·Faisal Abdullah KhasawnehJoseph Anthony Zorek
Nov 24, 2016·Acta neurochirurgica·Yuki YamagishiMotoo Nagane
Aug 26, 2014·World Journal of Gastroenterology : WJG·Grigoriy E Gurvits, Amy Tan
Oct 18, 2019·Journal of Clinical Pharmacy and Therapeutics·Shujuan ZhaoPeizhi Ma
Aug 13, 2013·The Pediatric Infectious Disease Journal·Theoni PetropoulouAthanasios Michos
Jun 14, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Leanne TeohMichael John McCullough

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