Bladder Contracture - A Rare and Serious Side Effect of Intravesical Bacillus Calmette-Guérin Therapy

Urology Case Reports
Cindy GarciaVenu Chalasani

Abstract

Instillation of intravesical bacillus Calmette-Guérin (BCG) is an effective treatment for non-muscle invasive bladder cancer (NMIBC). The high incidence of side effects may limit its tolerability in patients. Local side effects including cystitis and hematuria are common but generally self-limiting. Bladder contractures are a rare but serious consequence of BCG treatment. In this case, an 82 year-old male developed BCG reactivation and subsequent bladder contractures following transurethral resection of the prostate (TURP) three years post-BCG. To our knowledge, this is the first reported case of BCG reactivation post-TURP leading to the rare but serious effect of bladder contractures.

References

May 16, 2006·The Journal of Urology·Madhusudan P KoyaMark S Soloway
Jul 6, 2013·European Urology·Marko BabjukUNKNOWN European Association of Urology

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Methods Mentioned

BETA
biopsies

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