Bladder vs enteric drainage following pancreatic transplantation: How best to support graft survival? A best evidence topic

International Journal of Surgery
Nipuna V S Senaratne, Joseph M Norris

Abstract

A best evidence topic in transplant surgery was written according to a structured protocol. The question addressed was: In patients undergoing pancreatic transplantation alone, does enteric drainage or bladder drainage of exocrine secretions provide the best graft survival? A total of 155 papers were identified using the search protocol described, of which four retrospective cohort studies represented the best evidence available to answer the clinical question. The authors, journal, date and country of publication, study type, patient group studied, relevant outcomes and results of these papers are tabulated. Three of the four studies demonstrated no significant difference in graft survival between enteric drainage and bladder drainage at 6 months or 1 year. This included the largest and most recent study which showed that patient survival, graft survival and technical failure rates at 1 year were equal between the two duct management techniques. However, one study indicated lower graft survival at 1 year with enteric drainage due to a higher technical failure rate. Therefore, the clinical bottom line is that there is no significant difference in graft survival between enteric drainage or bladder drainage of pancreatic exocrine...Continue Reading

References

Mar 27, 2001·Transplantation Proceedings·R J CorryC A Vivas
Apr 17, 2001·Annals of Surgery·D E SutherlandJ S Najarian
Aug 19, 2011·International Journal of Surgery·Omar A KhanKevin Mackway-Jones
Jul 25, 2013·Diabetes Care·Rainer W G Gruessner, Angelika C Gruessner

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Citations

Jul 1, 2016·World Journal of Transplantation·Hany El-HennawyFowler Smith
Jan 14, 2021·World Journal of Transplantation·Joana Ferrer-Fàbrega, Laureano Fernández-Cruz
May 1, 2021·Journal of Clinical Medicine·Madhivanan Elango, Vassilios Papalois

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