Blastocoele expansion degree predicts live birth after single blastocyst transfer for fresh and vitrified/warmed single blastocyst transfer cycles

Fertility and Sterility
Qing-Yun DuYing-Pu Sun

Abstract

To evaluate the independent effects of the degree of blastocoele expansion and re-expansion and the inner cell mass (ICM) and trophectoderm (TE) grades on predicting live birth after fresh and vitrified/warmed single blastocyst transfer. Retrospective study. Reproductive medical center. Women undergoing 844 fresh and 370 vitrified/warmed single blastocyst transfer cycles. None. Live-birth rate correlated with blastocyst morphology parameters by logistic regression analysis and Spearman correlations analysis. The degree of blastocoele expansion and re-expansion was the only blastocyst morphology parameter that exhibited a significant ability to predict live birth in both fresh and vitrified/warmed single blastocyst transfer cycles respectively by multivariate logistic regression and Spearman correlations analysis. Although the ICM grade was significantly related to live birth in fresh cycles according to the univariate model, its effect was not maintained in the multivariate logistic analysis. In vitrified/warmed cycles, neither ICM nor TE grade was correlated with live birth by logistic regression analysis. This study is the first to confirm that the degree of blastocoele expansion and re-expansion is a better predictor of live...Continue Reading

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May 4, 2018·Human Fertility : Journal of the British Fertility Society·Avci BerrinUncu Gurkan
Aug 12, 2020·Archives of Gynecology and Obstetrics·Menghui LiBin Li
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Oct 5, 2020·Reproductive Biomedicine Online·Matthew A ShearAlan S Penzias
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Jul 14, 2021·Seminars in Cell & Developmental Biology·Julie Firmin, Jean-Léon Maître
Sep 22, 2021·Journal of Assisted Reproduction and Genetics·Hunter GiuncoDara S Berger

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