Blastocystis subtypes in cancer patients: Analysis of possible risk factors and clinical characteristics

Parasitology International
Ozlem YersalSema Ertuğ

Abstract

The aim of the present study was to examine the frequency and genetic diversity of Blastocystis in cancer patients of a Medical Oncology Department in Aydın, Turkey. Patients' stool samples were examined between January 2013 and February 2014 by both microscopy and culture methods. Culture positive samples were subjected to DNA isolation and Sequence Tagged Site (STS)-PCR analysis. Possible etiological factors and clinical features of Blastocystis infection were also analyzed and compared between Blastocystis infected and non-infected subgroups. Blastocystis was detected in 15 (6.5%) of 232 stool samples by microscopy and in 25 (10.8%) by culture methods. Out of 25 culture positive isolates, the most prevalent subtype was ST3 (59%), followed by ST1 (23%) and ST2 (18%). Blastocystis frequency was higher in the male patients than the females (19% vs. 6.5%, p<0.05) and in the patients living in urban areas than rural (15.3% vs. 6.6%, p<0.05). Interestingly, Blastocystis was more frequent in patients with lung cancer than the other cancer types (χ(2)=18, p<0.05) and also in the patients who had received at least eight chemotherapy cycles than fewer (21.4% vs. 9.9%, p<0.05). The rate of gastrointestinal symptoms was not significantl...Continue Reading

References

Jul 26, 2003·The Journal of Parasitology·Hisao YoshikawaYuzo Takahashi
Sep 24, 2004·The Korean Journal of Parasitology·Marta Cecilia MinvielleJuan Angel Basualdo
Oct 13, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J Klastersky, M Aoun
Mar 18, 2005·Parasitology Research·Aya TanizakiIsao Kimata
Aug 18, 2005·Journal of Gastroenterology and Hepatology·Karin LederRory Wolfe
Jul 14, 2007·Parasitology International·Lan-Hua LiLing Zhang
Oct 5, 2007·Diagnostic Microbiology and Infectious Disease·C Rune StensvoldHenrik V Nielsen
Mar 14, 2008·Parasitology International·Mustafa OzyurtChristen Rune Stensvold
Jun 5, 2008·Parasitology Research·Funda Dogruman-AlMete Demirel
Mar 18, 2009·Parasitology Research·Laetitia SouppartEric Viscogliosi
Apr 7, 2010·Parasitology International·Christian VogelbergChristoph Pöhlmann
Feb 5, 2011·The American Journal of Tropical Medicine and Hygiene·Tamalee RobertsDamien Stark
Feb 11, 2011·Current Infectious Disease Reports·Kevin S W TanPaul A Macary
Feb 15, 2012·Parasites & Vectors·Duangnate PipatsatitpongMathirut Mungthin
Feb 22, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Samudi ChandramathiUmah Rani Kuppusamy
Nov 2, 2012·Journal of Clinical Microbiology·Christen Rune Stensvold
Jun 19, 2013·Protist·Mohammed A AlfellaniC Graham Clark
Aug 13, 2013·Parasitology Research·Vinoth KumarasamySuresh Kumar
Aug 21, 2013·Tropical Parasitology·Christen Rune Stensvold
Oct 2, 2013·Trends in Parasitology·Pauline D Scanlan, Christen R Stensvold
Aug 29, 2014·Therapeutic Advances in Infectious Disease·Ivan WawrzyniakHicham El Alaoui
Jul 2, 2015·FEMS Microbiology Ecology·Lee O'Brien AndersenChristen Rune Stensvold

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Citations

Jan 3, 2021·Acta Parasitologica·Sefa MülayimMustafa Kaplan
Apr 16, 2021·Parasites & Vectors·Violetta Sulżyc-BielickaDariusz Bielicki
Sep 17, 2021·Environmental Science and Pollution Research International·Ali AsghariGholamreza Hatam

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