PMID: 6160899Sep 1, 1980Paper

Bleomycin and subsequent anaesthesia: a retrospective study at Vancouver General Hospital

Canadian Anaesthetists' Society Journal
M J Douglas, C M Coppin

Abstract

A retrospective review was made of 20 surgical procedures in 14 patients with testicular carcinoma, previously treated with bleomycin chemotherapy, to evaluate the incidence of postoperative pulmonary complications. Other studies have suggested an increased rate of pulmonary complications, including fatal respiratory failure, when inspired oxygen fraction (FIO2) exceeds 0.3 during or after operation. There is a suggestion that bleomycin may sensitize the lungs to the effect of oxygen, leading to oxygen toxicity. This study involved patients whose inspired oxygen fraction ranged from 0.3 to 1.0 and only one non-fatal pulmonary complication occurred. The risks of anaesthesia following bleomycin are discussed with particular reference to possible enhanced oxygen toxicity.

References

Jun 24, 1978·British Medical Journal·P L GoldinerW S Howland

❮ Previous
Next ❯

Citations

Jul 1, 1983·Canadian Anaesthetists' Society Journal·D S Klein, P R Wilds
Mar 1, 1984·Canadian Anaesthetists' Society Journal·D C OxornA M Lam
Apr 1, 1960·Canadian Anaesthetists' Society Journal·D MATHESON
Sep 1, 1995·Anesthesia and Analgesia·D D Mathes
Feb 4, 2014·Mayo Clinic Proceedings·Benjamin M AakreJohn H Eisenach
Jan 1, 1992·Chest·J WolkowiczC K Chan
Feb 1, 1991·Mayo Clinic Proceedings·T S IngrassiaE C Rosenow
Feb 5, 2002·Clinical Oncology : a Journal of the Royal College of Radiologists·R W TsangS Haley
Jan 3, 2015·Urologic Oncology·Hege S HaugnesRoy M Bremnes
Apr 1, 1991·Chest·M I Waid-Jones, D B Coursin
May 6, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hege S HaugnesRoy M Bremnes
Mar 5, 1989·Children's Health Care : Journal of the Association for the Care of Children's Health·P A JohnsonD J Brunnquell
Aug 9, 2003·Acta Anaesthesiologica Scandinavica·S Orbach-ZingerM Perouansky
Jan 1, 1990·Seminars in Surgical Oncology·S C Hall, G W Stevenson
Dec 1, 1985·Drug Intelligence & Clinical Pharmacy·R J CersosimoW K Hong
Feb 20, 1995·The Medical Journal of Australia·M J Jacka, C K Chan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.