PMID: 9181834Mar 1, 1997Paper

Blepharitis. Demodex folliculorum, associated pathogen spectrum and specific therapy

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
M DemmlerV Klauss

Abstract

Demodex folliculorum has been demonstrated with an elevated frequency in patients with blepharitis, and is thought to cause therapy-resistant blepharitis. This paper presents the germ spectrum of patients with blepharitis and demodex and discusses the efficiency of a specific therapy. In all, 3152 cilia from 139 patients with blepharitis (38% blepharitis, 44% blepharoconjunctivitis, others) and 108 persons with quiet eyes were examined for demodex. Smears n = 125, from the conjunctive of symptomatic patients were investigated for bacteria, 3 weeks of therapy with mercury ointment, 2%: Lindan, cortisone (prednisolone, dexamethasone, hydrocortisone, fluorometholone) or antibiotics after antibiogram (gentamicin, kanamicin, neomicin, erythromicin, ofloxacin, polymyxin-B, colistin) followed in all Demodex-positive blepharitis patients (n = 41). Demodex was found in 52% (62/139) of patients with chronic blepharitis, as against 20% (3/15) of those with acute blepharitis (statistically significant difference, chi 2-test, alpha = 2.5%) and in 29% of quiet eyes (statistically significantly less, alpha = 2.5%, chi 2-test). Gram-positive cocci were isolated from 79% of 57 Demodex-positive patients with blepharitis and 72% of 68 Demodex-neg...Continue Reading

Citations

Mar 18, 2009·Cytopathology : Official Journal of the British Society for Clinical Cytology·S DivaniD Kapsalas
May 30, 2013·Ophthalmic Epidemiology·Danuta I Kosik-BogackaElżbieta Kalisińska
Jul 22, 2005·Ophthalmic Epidemiology·Mustafa KemalMakbule Akbulut
Dec 20, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C CursiefenF E Kruse
Mar 1, 2012·Ophthalmic Epidemiology·Ya-E ZhaoJi-Ru Xu
Jul 4, 2003·International Journal of Dermatology·Zülal ErbagciSuna Erkiliç
Dec 19, 2013·Translational Vision Science & Technology·Sean TigheScheffer C G Tseng
Jul 3, 2010·Bulletin de la Société de pathologie exotique·F CheikhrouhouA Ayadi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.